Homocysteine in Health and Disease

Herausgeber: Carmel, Ralph; Jacobsen, Donald W.

• Broschiertes Buch

Produktbeschreibung

This is an unusually comprehensive 2001 account of the broad range of medical implications of homocysteine.

Produktdetails

• Verlag: Cambridge University Press
• Seitenzahl: 536
• Erscheinungstermin: 7. September 2011
• Englisch
• Abmessung: 280mm x 210mm x 29mm
• Gewicht: 1295g
• ISBN-13: 9781107402423
• ISBN-10: 1107402425
• Artikelnr.: 34570785

Inhaltsangabe

1. Introduction: historical overview and recent perspectives David Wilken
and Bridget Wilken; Part I. Biochemistry and Physiology; Section I.
Chemistry: 2. Practical chemistry of homocysteine and other thiols Donald
W. Jacobsen; 3. Biosynthesis and reactions of homocysteine thiolactone
Hieronim Jakubowski; 4. Homocysteine and lipid oxidation Jay W. Heinecke;
5. Homocysteine, nitric oxide and nitrosothiols Andrew J. Gow, Fred Cobb
and Jonathan S. Stamler; Section II. Biochemistry and metabolism: 6.
Biosynthesis of S-adenosylmethionine Jose M. Mato, Matias A. Avila and
Fernado J. Corrales; 7. S-adenosylmethionine-dependent methyltransferase
Steven G. Clarke and Kelly Banfield; 8. S-adenosylhomosysteine hydrolase
Sean T. Prigge and Peter K. Chiang; 9. Regulation of homocysteine
metabolism James D. Finkelstein; 10. Microbial modeling of human disease:
homocysteine metabolism Rowena G. Matthews and Martha L. Ludwig; 11. Folate
metabolism Robert J. Cook; 12. Cobalamin-dependent remethylation Ruma V.
Banerjee and Horatiu Olteanu; 13. Betaine-dependent remethylation Tim
Garrow; 14. The transsulfuration pathway Warren D. Kruger; Section III.
Physiology: 15. Cellular transport and tissue distribution Brian Fowler;
16. Homocysteine and the kidney John T. Brosnan; 17. Homocysteine and the
nervous system Anne M. Molloy and Donald G. Weir; Section IV. Clinical
Chemistry: 18. Methodologies of testing Karsten Rasmussen and Jan Möller;
19. Methionine loading Nicholas Dudman and Jonathan Silberberg; Part II.
Clinical Dysfunction and Hyperhomocysteinemia; Section V. Genetic
Disorders: 20. Cystathionine-ß-synthase and its deficiency Jan P. Kraus and
Viktor Kozich; 21. Inborn errors of folate and cobalamin metabolism David
S. Rosenblatt; 22. Polymorphisms of folate and cobalamin metabolism Rima
Rozen; Section VI. Acquired Disorders: 23. Folate deficiency Ralph Carmel;
24. Cobalamin deficiency Ralph Carmel; 25. Vitamin B6 deficiency Jesse F.
Gregory III; 26. Homocysteine in renal disease Margret Arnadottir and Björn
Hultberg; 27. Diseases and drugs associated with hyperhomocysteinemia Henk
J. Blom; 28. Lifestyle factors associated with hyperhomocysteinemia Stein
Emil Vollset, Helga Refsum, Ottar Nygard and Per Ueland; Section VII.
Clinical Consequences of Hyperhomocysteinemia: 29. Epidemiology: vascular
and thrombotic associations Petra Verhoef and Meir Stampfer; 30.
Homocysteine and coronary artery disease Killian Robinson; 31. Homocysteine
and cerebrovascular disease J. David Spence and James F. Toole; 32.
Peripheral arterial disease Godfried Boers; 33. Venous disease Armando
D'Angelo and Chiara Beltrametti; 34. Homocysteine and hemostasis Katherine
A. Hajjar; 35. Cellular mechanisms of homocysteine pathogenesis in
atherosclerosis Donald W. Jacobsen; 36. Homocysteine and cardiovascular
physiology Steven R. Lentz; 37. Homocysteine and human reproduction T. K.
A. B. Eskes; Section VIII. Intervention and Therapy: 38. Modification of
hyperhomocysteinemia John M. Scott; 39. Design of clinical trials to test
the homocysteine hypothesis of vascular disease Robert Clarke; 40. What is
a desirable homocysteine level? Johan B. Ubbink; Index.