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Diabetes mellitus or simply diabetes, is a metabolic of disorder portrayed by high blood glucose/sugar levels (hyperglycemia) that outcome from imperfections in the body's ability to produce and/or use insulin. Conventional system of medicine is able to control and prevent the further progression of diabetes mellitus but unable to cure the disease. For this reason systematic clinical study as required for efficacious treatment of diabetes. Keeping this in view this study was undertaken so as to outline a scientific approach that could be applied for homoeopathic treatment of diabetes mellitus. Homoeopathic treatment can enhance all dimensions of wellbeing i.e. mental, physical, environmental aspects, and social, not simple annihilation of physical manifestations.