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There is a need to implement early-life predictors of allergic sensitization, so that at-risk newborns can be accurately defined and preventive measures instituted. The work presented in this book gives an in-sight into the possibility of in utero allergen exposure of the fetus in allergic and non-allergic mothers and suggests that maternal environmental exposure influences innate immune functions of the newborn. Three main findings can be emphasized. First, in-utero exposure to HDM allergens Der p1 & Blo t5 is prevalent, second, in-utero T-cell helper function imbalance due to in-utero…mehr

Produktbeschreibung
There is a need to implement early-life predictors of allergic sensitization, so that at-risk newborns can be accurately defined and preventive measures instituted. The work presented in this book gives an in-sight into the possibility of in utero allergen exposure of the fetus in allergic and non-allergic mothers and suggests that maternal environmental exposure influences innate immune functions of the newborn. Three main findings can be emphasized. First, in-utero exposure to HDM allergens Der p1 & Blo t5 is prevalent, second, in-utero T-cell helper function imbalance due to in-utero allergen exposure and third, the newborn may already be on the way to the development of allergic disease.
Autorenporträt
La Dra. Shilpa Shah es investigadora en el campo de la alergia y la inmunología. Se le concedió un doctorado de la Universidad de Mumbai por su trabajo publicado en el presente libro. Durante la investigación posdoctoral trabajó en la Universidad de Texas, Austin, EE. UU.