Tomato is one of the most important vegetable crop in Ethiopia. Diseases are major constraints that limit production of tomato in the country. Late blight is a very severe disease in most tomato-growing regions, including the Gamo Gofa Zone, where information on disease management options through integration of varieties and fungicide applications are inadequate. This book contributes to the extensive studies needed for developing concrete recommendation for late blight management options through integration of varieties and fungicide applications that may contribute to sustainability by stabilizing tomato production in the country.