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The endosymbiotic archaea produces an endogenous membrane sodium-potassium ATPase inhibitor, digoxin. Digoxin levels and membrane sodium-potassium ATPase activity is related to psychological states like spirituality, bonding and affection, hypo/hyper/homo sexual states, various levels of appetite and sleep, creativity and addiction. Digoxin secretion and hemispheric dominance are related. Hyperdigoxinemia is related to right hemispheric dominance and hypodigoxinemia left hemispheric dominance.