Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the "novel" nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public…mehr
Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the "novel" nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.
THE EDITOR Sunit K. Singh, Ph.D is an Associate Professor (Molecular Immunology) in the Molecular Biology Unit, Faculty of Medicine, Institute of Medical Sciences, Banaras Hindu University (BHU), Varanasi, India.
Inhaltsangabe
List of Contributors ix Preface xvii Acknowledgments xix About the Editor xxi 1 Pathogenesis of the OldWorld Arenaviruses in Humans 1 Igor S. Lukashevich 2 Pathogenesis of New World Arenaviruses in Humans 29 Verónica Martín Stefan Kunz Esteban Domingo and Noemí Sevilla 3 Pathogenesis of Emerging and Novel Bunyaviruses in Humans 43 Cong Jin and Dexin Li 4 Pathogenesis of Rift Valley Fever in Humans 73 Inaia Phoenix and Tetsuro Ikegami 5 Pathogenesis of Hantavirus Infections 95 Tarja Sironen Olli Vapalahti and Alexander Plyusnin 6 Molecular Pathogenesis of Japanese Encephalitis Virus Infection 113 Sunit Kumar Singh 7 Dengue Virus Infection in Humans: Epidemiology Biology Pathogenesis and Clinical Aspects 125 Fatih Anfasa Leonard Nainggolan and Byron E. E. Martina 8 Pathogenesis of West Nile Virus in Humans 145 Rianna Vandergaast Katherine L. Hussmann and Brenda L. Fredericksen 9 Overview on Chikungunya Virus Pathogenesis 177 Sunit Kumar Singh 10 Nipah Virus Infections in Humans 189 Kaw Bing Chua Chong Tin Tan and Kum Thong Wong 11 Pathogenesis of Hendra Virus in Humans 207 Chad E. Mire Benjamin A. Satterfield and Thomas W. Geisbert 12 Pathogenesis of Rotavirus in Humans 227 Carlos Fernando Narváez Martha C. Mesa Alfonso Barreto Luz-Stella Rodríguez and Juana Angel 13 Pathogenesis of Papillomaviruses in Humans 243 John Doorbar 14 Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis 265 Lia R. Walker Anshul V. Subramanya Zeal T. Akula and Shaw M. Akula 15 Microsporidiosis in Humans 281 Henry Shikani Elizabeth S. Didier and Louis M. Weiss 16 Pathogenesis of Toxoplasma gondii in Humans 303 Hong-Juan Peng Feng Tan and David S. Lindsay 17 Pathogenesis of Human African Trypanosomiasis 319 Jennifer Cnops and Stefan Magez 18 Pathogenesis of Leishmaniasis in Humans 337 Steve Oghumu Gayathri Natarajan and Abhay R. Satoskar 19 Pathogenesis of Chagas Disease in Humans 349 María-Jesús Pinazo Faustino Torrico and Joaquim Gascón 20 Pathogenesis of Cryptosporidium in Humans 371 Gabriela Certad Marwan Osman and Sadia Benamrouz 21 Pathogenesis of Malarial Parasites in Humans 393 Caroline Lin Lin Chua Ricardo Ataíde Alexandra J. Umbers and Phillipe Boeuf 22 Pathogenesis of Trichomonas vaginalis in Humans 423 Marlene Benchimol Antonio Pereira-Neves and Wanderley de Souza 23 Loa loa Pathogenesis in Humans 441 Akue Jean Paul 24 Nematode LarvaMigrans 453 Kumara Singaravelu Christina M. Coyle Yuri C. Martins Louis M. Weiss Fabiana S. Machado Herbert B. Tanowitz and Kevin R. Kazacos 25 Pathogenesis of Human Schistosomiasis 481 Thien-Linh Le Susanne H. Sokolow Olfat Hammam Chi-Ling Fu and Michael Hsieh 26 Vector-Borne Parasitic Zoonotic Infections in Humans 505 Domenico Otranto and Filipe Dantas-Torres Index i
List of Contributors ix Preface xvii Acknowledgments xix About the Editor xxi 1 Pathogenesis of the OldWorld Arenaviruses in Humans 1 Igor S. Lukashevich 2 Pathogenesis of New World Arenaviruses in Humans 29 Verónica Martín Stefan Kunz Esteban Domingo and Noemí Sevilla 3 Pathogenesis of Emerging and Novel Bunyaviruses in Humans 43 Cong Jin and Dexin Li 4 Pathogenesis of Rift Valley Fever in Humans 73 Inaia Phoenix and Tetsuro Ikegami 5 Pathogenesis of Hantavirus Infections 95 Tarja Sironen Olli Vapalahti and Alexander Plyusnin 6 Molecular Pathogenesis of Japanese Encephalitis Virus Infection 113 Sunit Kumar Singh 7 Dengue Virus Infection in Humans: Epidemiology Biology Pathogenesis and Clinical Aspects 125 Fatih Anfasa Leonard Nainggolan and Byron E. E. Martina 8 Pathogenesis of West Nile Virus in Humans 145 Rianna Vandergaast Katherine L. Hussmann and Brenda L. Fredericksen 9 Overview on Chikungunya Virus Pathogenesis 177 Sunit Kumar Singh 10 Nipah Virus Infections in Humans 189 Kaw Bing Chua Chong Tin Tan and Kum Thong Wong 11 Pathogenesis of Hendra Virus in Humans 207 Chad E. Mire Benjamin A. Satterfield and Thomas W. Geisbert 12 Pathogenesis of Rotavirus in Humans 227 Carlos Fernando Narváez Martha C. Mesa Alfonso Barreto Luz-Stella Rodríguez and Juana Angel 13 Pathogenesis of Papillomaviruses in Humans 243 John Doorbar 14 Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis 265 Lia R. Walker Anshul V. Subramanya Zeal T. Akula and Shaw M. Akula 15 Microsporidiosis in Humans 281 Henry Shikani Elizabeth S. Didier and Louis M. Weiss 16 Pathogenesis of Toxoplasma gondii in Humans 303 Hong-Juan Peng Feng Tan and David S. Lindsay 17 Pathogenesis of Human African Trypanosomiasis 319 Jennifer Cnops and Stefan Magez 18 Pathogenesis of Leishmaniasis in Humans 337 Steve Oghumu Gayathri Natarajan and Abhay R. Satoskar 19 Pathogenesis of Chagas Disease in Humans 349 María-Jesús Pinazo Faustino Torrico and Joaquim Gascón 20 Pathogenesis of Cryptosporidium in Humans 371 Gabriela Certad Marwan Osman and Sadia Benamrouz 21 Pathogenesis of Malarial Parasites in Humans 393 Caroline Lin Lin Chua Ricardo Ataíde Alexandra J. Umbers and Phillipe Boeuf 22 Pathogenesis of Trichomonas vaginalis in Humans 423 Marlene Benchimol Antonio Pereira-Neves and Wanderley de Souza 23 Loa loa Pathogenesis in Humans 441 Akue Jean Paul 24 Nematode LarvaMigrans 453 Kumara Singaravelu Christina M. Coyle Yuri C. Martins Louis M. Weiss Fabiana S. Machado Herbert B. Tanowitz and Kevin R. Kazacos 25 Pathogenesis of Human Schistosomiasis 481 Thien-Linh Le Susanne H. Sokolow Olfat Hammam Chi-Ling Fu and Michael Hsieh 26 Vector-Borne Parasitic Zoonotic Infections in Humans 505 Domenico Otranto and Filipe Dantas-Torres Index i
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