Human Prion Diseases
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Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more…mehr

Produktbeschreibung
Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems.

Offers an authoritative overview of prion diseases in humans, detailing the pathogenesis of the disease, clinical investigations, and the diagnosis of both the genetic and acquired forms
Provides clarity and context by presenting prion diseases in relation to other neurodegenerative diseases in humans
Emphasizes the unique properties of prion diseases and consequent problems they can cause, both clinically and in public health terms
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Autorenporträt
Pocchiari, Maurizio
Professor Maurizio Pocchiari is a neurologist working at the Istituto Superiore di Sanità, Rome, Italy, where chairs the Department of Neuroscience. He heads a group of neurologists, geneticists, biochemists, and statisticians working on various aspects of human and experimental prion diseases. These include studies on clinical and molecular epidemiology, diagnosis, pathogenesis, experimental therapy, biochemistry and molecular and cellular biology of the prion protein and the prion protein gene, development of new techniques for the inactivation of prions, and the analysis of risk in transmitting prions from animal-to-human or from human-to-human. Professor Pocchiari runs the Italian Creutzfeldt-Jakob disease surveillance unit since 1993 and is a member of the Coordination Committee of the European Creutzfeldt-Jakob disease Surveillance Network (EuroCJD) of the European Centre for Disease Prevention and Control (ECDC).