This assessment on hydrochemistry is a perfect and precise guide to understanding the hydrogeology, as well as the variational changes affecting groundwater quality in Legon campus. Standardized procedures and analysis are explicitly outlined to explain all terms and figures. Extensive exponential rise into urbanization over the years has led to massive degradation of surface water resources, hence, groundwater is harnessed in larger volumes for all purposes with little, or no regard to quality. Considering the substantial land use changes and the higher rate of groundwater consumption in Legon campus, there is therefore, the conscious need to undertake comprehensive groundwater sampling to understand the hydrochemistry and the quality aspect of the water. This guide is therefore, indispensable for geoscientists who wish to gain in-depth insight in the hydrochemistry of Legon, Accra.