Hypoxia and Consequences, Volume 1177

Herausgegeben von Peers, Chris; Haddad, Gabriel G.; Chandel, Navdeep S.

• Broschiertes Buch

Produktbeschreibung

International experts from academia, industry and government discuss the cellular mechanisms that underlie rapid and delayed responses to oxygen deprivation, known as hypoxia. This volume brings together researchers and clinicians from developmental and cellular biology, drug development, oncology, neurobiology and medicine to discuss 1) How hypoxia-inducible factors regulate development and physiology, 2) How cells sense changes in oxygen availability, and 3) How oxygen availability affects several pathologies like pulmonary hypertension, sleep apnea, cancer and neurodegeneration.

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Produktdetails

• Annals of the New York Academy of Sciences .1177
• Verlag: Wiley & Sons
• 1. Auflage
• Seitenzahl: 352
• Erscheinungstermin: 23. November 2009
• Englisch
• Abmessung: 249mm x 175mm x 10mm
• Gewicht: 460g
• ISBN-13: 9781573317733
• ISBN-10: 157331773X
• Artikelnr.: 28707876

Autorenporträt

Chris Peers and Gabriel G. Haddad are the authors of Hypoxia and Consequences, Volume 1177, published by Wiley.

Inhaltsangabe

Introduction to Hypoxia and Consequences: From Molecule to Malady (Chris Peers
Navdeep S. Chandel
Gabriel G. Haddad). Part I. Transcriptional Responses to Hypoxia. 1. Regulation of Vascularization by Hypoxia-Inducible Factor 1 (Gregg L. Semenza). 2. FIH-Dependent Asparaginyl Hydroxylation of Ankyrin Repeat Domain-Containing Proteins (Matthew E. Cockman
James D. Webb
Peter J. Ratcliffe). 3. From Polyps to People: A HIghly Familiar Response to Hypoxia (R.J. Hampton-Smith
D.J. Peet). 4. Maintaining Mammalian Iron and Oxygen Homeostasis: Sensors
Regulation
and Cross-Talk (Ameen A. Salahudeen
Richard K. Bruick). 5. Survival in Acute and Severe Low O2 Environment: Use of a Genetic Model System (Priti Azad
Gabriel G. Haddad). 6. Mitochondria and Hypoxic Signaling: A New View (Robert O. Poyton
Pablo R. Castello
Kerri A. Ball
Dong Kyun Woo
Ning Pan). 7. Pathophysiological Consequences of HIF Activation: HIF as a Modulator of Fibrosis (Volker H. Haase). 8. Mitochondrial Metabolism and Cancer (Frank Weinberg
Navdeep S. Chandel ). Part II. Oxygen Sensing. 9. Molecular Imaging: Into In Vivo Interaction of HIF-1 and HIF-2 with ARNT (Rebecca Konietzny
Anna König
Christoph Wotzlaw
André Bernadini
Utta Berchner-Pfannschmidt
Joachim Fandrey). 10. Oxygen-Sensitive Potassium Channels in Chemoreceptor Cell Physiology: Making a Virtue of Necessity (Constancio Gonzalez
Luis M. Vaquero
José Ramón López-López
M. Teresa Pérez-García). 11. Ion Channel Regulation by AMPK: The Route of Hypoxia-Response Coupling in the Carotid Body and Pulmonary Artery (A. Mark Evans
D. Grahame Hardie
Chris Peers
Christopher N. Wyatt
Benoit Viollet
Prem Kumar
Mark L. Dallas
Fiona Ross
Naoko Ikematsu
Heidi L. Jordan
Barbara L. Barr
J. Nicole Rafferty
Oluseye Ogunbayo). 12. Hypoxia Selectively Inhibits KCNA5 Channels in Pulmonary Artery Smooth Muscle Cells (Amy L. Firth
Oleksandr Platoshyn
Elena E. Brevnova
Elyssa D. Burg
Frank Powell
Gabriel H. Haddad
Jason X.-J. Yuan). 13. Enzyme-Linked Oxygen Sensing by Potassium Channels (Paul J. Kemp
Vsevolod Telezhkin
William J. Wilkinson
Ruth Mears
Stuart B. Hanmer
Hanne C. Gadeberg
Carsten T. Müller
Daniela Riccardi
Stephen P. Brazier ). 14. Oxygen Sensing in the Carotid Body (José López-Barneo
Patricia Ortega-Sáenz
Ricardo Pardal
Alberto Pascual
José I. Piruat
Rocío Durán
Raquel Gómez-Díaz). 15. Regulation of Oxygen Sensitivity in Adrenal Chromaffin Cells (Colin A. Nurse
Josef Buttigieg
Stephen Brown
Alison C. Holloway). 16. Oxidative DNA Modifications in Hypoxic Signaling (Mark N. Gillespie
Viktor Pastukh
Mykhaylo V. Ruchko). 17. The Neuronal Control of Hypoxic Ventilation: Erythropoietin and Sexual Dimorphism (Max Gassmann
Martha Tissot van Patot
Jorge Soliz). Part III. Pathophysiological Responses to Hypoxia. 18. Intermittent Hypoxia-Mediated Plasticity of Acute O2 Sensing Requires Altered Red-Ox Regulation by HIF-1 and HIF-2 (Nanduri R. Prabhakar
Ganesh K. Kumar
Jayasri Nanduri). 19. Hypoxia and Neurodegeneration (Chris Peers
Mark L. Dallas
Hannah E. Boycott
Jason L. Scragg
Hugh A. Pearson
John P. Boyle). 20. The Role of NF-B in Hypoxia-Induced Gene Expression (Cormac T. Taylor
Eoin P. Cummins). 21. Role of Hypoxia-Inducible Factors in Epigenetic Regulation via Histone Demethylases (Jun Yang
Ioanna Ledaki
Helen Turley
Kevin C. Gatter
Juan-Carlos Martinez Montero
Ji-Liang Li
Adrian L. Harris). 22. An Essential Role of the HIF-1-c-Myc Axis in Malignant Progression ( Young-Gun Yoo
Masami Hayashi
Jared Christensen
L. Eric Huang).