Providing a comprehensive and critical review of the basic science and clinical aspects of the drug, this book covers the history and development of the drug and its current patterns of use and examines its basic pharmaceutical attributes and medicinal chemistry. The author discusses the properties of various formulations and discusses the pharmacokinetics of ibuprofen in animals and humans--highlighting the factors affecting absorption, distribution, metabolism, and elimination. Topics include: the clinical pharmacology and toxicology and the drug's mechanisms of action in different disease…mehr
Providing a comprehensive and critical review of the basic science and clinical aspects of the drug, this book covers the history and development of the drug and its current patterns of use and examines its basic pharmaceutical attributes and medicinal chemistry. The author discusses the properties of various formulations and discusses the pharmacokinetics of ibuprofen in animals and humans--highlighting the factors affecting absorption, distribution, metabolism, and elimination. Topics include: the clinical pharmacology and toxicology and the drug's mechanisms of action in different disease states and conditions, the therapeutic uses in various acute and inflammatory conditions, and safety versus efficacy issues and the pharmacoepidemiological data.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Kim Rainsford is Professor and Chair of Biomedical Sciences and Director of the Biomedical Research Centre at Sheffield Hallam University, UK. His research interests lie mainly in mechanisms of inflammation and the mode of action of anti-inflammatory and anti-arthritic drugs. He has published many books and journal articles and is frequently invited to speak at major international conferences and meetings.
Inhaltsangabe
1. History and Development of Ibuprofen K.D. Rainsford 2. The Medicinal Chemistry of Ibuprofen K.J. Nichol 3. The Pharmaceutics of Ibuprofen F. Higton 4. The Pharmacokinetcs of Ibuprofen in Humans and Animals D.R. Brocks and F. Jamaili 5. Pharmacology and Toxicology of Ibuprofen K.D. Rainsford 6. Therapeutics of Ibuprofen in Rheumatic and Other Chronic and Painful Diseases W.F. Kean W.W. Buchanan and K.D. Rainsford 7. Safety and Efficacy of Non-Prescription (OTC) Ibuprofen K.D. Rainsford 8. Use of Ibuprofen in Dentistry R.A. Dionne and S.A. Cooper 9. Gastrointestinal Adverse Drug Reactions Attributed to Ibuprofen D.A. Henry A. Drew and S. Beuzeville 10. Renal Effects of Ibuprofen M.D. Murray and D.C. Brater 11. Adverse Drug Reactions Attributed to Ibuprofen: Effects Other Than Gastrointestinal L.J. Miwa and J.K. Jones 12. Human Toxicity of Ibuprofen G.N. Volans and R. Fitzpatrick Nichol Boots Pharmaceuticals UK F. Higton Boots Healthcare International D.R. Brock Western University of Health Sciences USA F. Jamaili University of Alberta USA W.F. Kean McMaster University Canada W.W. Buchanan Sir William Osler Health Institute Canada R.A. Dionne National Istitute of Health USA S.A. Cooper Whitehall-Robins Health Care USA D.A. Henry Newcastle Mater Hospital Australia A. Drew Newcastle Mater Hospital Australia S. Beuzeville Newcastle Mater Hospital Australia M.D. Murray Regenstrief Health Centre USA D.C. Brater Indiana university School of Medicine USA L.J. Miwa The Degge Group USA J.K. Jones The Degge Group USA G.N. Volans Guys and St. Thomas' Hospital Trust UK R. Fitzpatrick Guys and St. Thomas' Hospital Trust UK.
1. History and Development of Ibuprofen K.D. Rainsford 2. The Medicinal Chemistry of Ibuprofen K.J. Nichol 3. The Pharmaceutics of Ibuprofen F. Higton 4. The Pharmacokinetcs of Ibuprofen in Humans and Animals D.R. Brocks and F. Jamaili 5. Pharmacology and Toxicology of Ibuprofen K.D. Rainsford 6. Therapeutics of Ibuprofen in Rheumatic and Other Chronic and Painful Diseases W.F. Kean W.W. Buchanan and K.D. Rainsford 7. Safety and Efficacy of Non-Prescription (OTC) Ibuprofen K.D. Rainsford 8. Use of Ibuprofen in Dentistry R.A. Dionne and S.A. Cooper 9. Gastrointestinal Adverse Drug Reactions Attributed to Ibuprofen D.A. Henry A. Drew and S. Beuzeville 10. Renal Effects of Ibuprofen M.D. Murray and D.C. Brater 11. Adverse Drug Reactions Attributed to Ibuprofen: Effects Other Than Gastrointestinal L.J. Miwa and J.K. Jones 12. Human Toxicity of Ibuprofen G.N. Volans and R. Fitzpatrick Nichol Boots Pharmaceuticals UK F. Higton Boots Healthcare International D.R. Brock Western University of Health Sciences USA F. Jamaili University of Alberta USA W.F. Kean McMaster University Canada W.W. Buchanan Sir William Osler Health Institute Canada R.A. Dionne National Istitute of Health USA S.A. Cooper Whitehall-Robins Health Care USA D.A. Henry Newcastle Mater Hospital Australia A. Drew Newcastle Mater Hospital Australia S. Beuzeville Newcastle Mater Hospital Australia M.D. Murray Regenstrief Health Centre USA D.C. Brater Indiana university School of Medicine USA L.J. Miwa The Degge Group USA J.K. Jones The Degge Group USA G.N. Volans Guys and St. Thomas' Hospital Trust UK R. Fitzpatrick Guys and St. Thomas' Hospital Trust UK.
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