Andere Kunden interessierten sich auch für
![Three Branches of Theories of Financial Crises]( "Three Branches of Theories of Financial Crises")
Three Branches of Theories of Financial Crises72,99 €![Meat Three Times a Day]( "Meat Three Times a Day")
Meat Three Times a Day36,99 €![Coffin's Interest Tables At One-half, One, Two, Three, Three-and-one Half, Four, Four-and-one-half, Five, Six, Seven, Eight And Ten Per-cent, Per Annu]( "Coffin's Interest Tables At One-half, One, Two, Three, Three-and-one Half, Four, Four-and-one-half, Five, Six, Seven, Eight And Ten Per-cent, Per Annu")
Coffin's Interest Tables At One-half, One, Two, Three, Three-and-one Half, Four, Four-and-one-half, Five, Six, Seven, Eight And Ten Per-cent, Per Annu35,99 €![Adaptation of three layer breeds in the tropics]( "Adaptation of three layer breeds in the tropics")
Adaptation of three layer breeds in the tropics17,99 €![Multilingual Signature Identification & Verification in Forgery Domain]( "Multilingual Signature Identification & Verification in Forgery Domain")
Multilingual Signature Identification & Verification in Forgery Domain24,99 €![Identification of a reliable credit borrower]( "Identification of a reliable credit borrower")
Identification of a reliable credit borrower46,99 €![Three days coronavirUS in my head]( "Three days coronavirUS in my head")
Three days coronavirUS in my head8,99 €
Maple Syrup Urine Disease (MSUD) is a genetically heterogeneous metabolic disorder that is transmitted in an autosomal recessive manner. According to clinical data, MSUD prevalence in Lebanon is expected to be higher than the International prevalence because of consanguineous marriage. Novel mutations are still getting detected by using DNA sequencing for mutation analysis in MSUD patients. In the current study, we have extracted DNA from Lebanese MSUD patients in order to amplify the exonic and flanking intronic regions of the genes implicated in MSUD (BCKDHA, BCKDHB, and DBT) and sequenced the resultant amplified products to assess the molecular genetics of MSUD in the Lebanese population studied. All of the mutations identified occurred in the homozygous state, which reflects the high rate of consanguineous marriage in Lebanon. In the current study, we have identified one previously cited mutation and three novel mutations not previously described in the scientific literature.The majority of the mutations identified in the Lebanese MSUD patients occurred in the DBT gene. Consanguineous marriage is a major risk factor for the prevalence of MSUD in Lebanon.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.