This book is a comprehensive resource on using mass spectrometry proteomics (MSP), a powerful new technique combining hardware and software, as a highly accurate means for the detection, identification, and classification of microbes including unknown or unsequenced bacteria, viruses, and fungi. Chapters describe various mass analyzers, methods for analyzing MS data files, genomic approaches, sample collection and processing, software and bioinformatics, and examples of application of the method. This book also surveys commercially available MS-based platforms suitable for MSP and discusses future trends in these groundbreaking techniques.…mehr
This book is a comprehensive resource on using mass spectrometry proteomics (MSP), a powerful new technique combining hardware and software, as a highly accurate means for the detection, identification, and classification of microbes including unknown or unsequenced bacteria, viruses, and fungi. Chapters describe various mass analyzers, methods for analyzing MS data files, genomic approaches, sample collection and processing, software and bioinformatics, and examples of application of the method. This book also surveys commercially available MS-based platforms suitable for MSP and discusses future trends in these groundbreaking techniques.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Dr. Charles H. Wick, Ph.D., is a retired senior scientist from the U.S. Army Edgewood Chemical Biological Center, where he has served both as a manager and research physical scientist and has made significant contributions to forensic science. Although his 40-year professional career has spanned both the public sector and the military, his better-known work in the area of forensic science has occurred in concert with the Department of Defense. Throughout his career, Dr. Wick has made lasting and important contributions to forensic science and to the field of antiterrorism. He holds several U.S. patents in the area of microbe detection and classification. He has written more than 45 civilian and military publications and has received myriad awards and citations.
Inhaltsangabe
Detection and Identification of Microbes Using Mass Spectrometry Proteomics. Mass Analyzers and MS/MS Methods for Microbial Detection and Identification. Matching Mass Spectral Profiles of Biomarkers. Sequence Information Derived from Proteins or Nucleic Acids. Collection and Processing of Microbial Samples. Computer Software Used for Chemometric and Bioinformatics to Discriminate Microbes. Applications. Survey of Commercially Available MS-Based Platforms Suitable for Bacterial Detection and Identification. Current and Future Trends in Using MS for Microbial Detection and Identification. References. Index.
Detection and Identification of Microbes Using Mass Spectrometry Proteomics. Mass Analyzers and MS/MS Methods for Microbial Detection and Identification. Matching Mass Spectral Profiles of Biomarkers. Sequence Information Derived from Proteins or Nucleic Acids. Collection and Processing of Microbial Samples. Computer Software Used for Chemometric and Bioinformatics to Discriminate Microbes. Applications. Survey of Commercially Available MS-Based Platforms Suitable for Bacterial Detection and Identification. Current and Future Trends in Using MS for Microbial Detection and Identification. References. Index.
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