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This study will take you to the next level in the approach to deep seated lesions apart from basic ideas. It almost covers all the possible deep seated lesions and their differential diagnosis with morphology and immunocytochemistry. Relevant gross pictures & microphotographs of pre operative cytology and post operative histopathology slides also added. The choice of immunocytochemical markers also included along with schematic approach.It will boost the confidence level of fresh budding Pathologists and post graduate students.