This book contains the new image processing algorithm technique for breast cancer detection.The image processing consists of three major steps i.e. pre-processing, segmentation and finally features extraction along with classification for both MIAS Bench mark data set and a novel regional database named as "I- MI Data Base" developed for the Indian Women. This book includes development of a regional dataset available in DICOM format collected from various leading hospitals; a Metadata is converted to BMP format and created a Regional Benchmark database named as "I-MI Database". The novelty of this research work is the application of a new feature based machine learning algorithm to categorize the mammogram images as benign and malignant for a novel data base I- MI.