In this book, we investigate a super-pixel based scheme that integrates both image segmentation and mesh generation into a single method, making mesh generation truly an image-incorporated approach. Our method, called image content-aware mesh generation, consists of several main steps. First, we generate a set of feature-sensitive and adaptively distributed points from 2D grayscale images or 3D volumes. Second, a Delaunay-triangulation generator (2D) or tetrahedral mesh generator (3D) is then utilized to generate a 2D triangulation or 3D tetrahedral mesh. A graph-cut method is then applied to the graph to define the boundary between two subsets of the graph, resulting in good boundary segmentations with high-quality meshes.