Imaging and the Aging Brain, Volume 1097

Ed. by Mony J. de Leon, Donald A. Snider and Howard Federoff

• Broschiertes Buch

Produktbeschreibung

Advances in imaging are occurring at a brisk pace, and imaging techniques have great potential to act as pre-symptomatic predictors of disease as well as to chart the course of a disease. Neuroimaging has greatly advanced the understanding of brain function and its relationship to the anatomical substrate. This volume brings together internationally renowned imaging scientists, those studying the aging brain, industry experts, and clinicians to jointly examine the most current methods and their application to brain physiology, behavior, and age-related diseases.
These reports explore new technologies, data from recent neuroimaging initiatives, and translational research applications. Topics covered include (1) in vivo imaging of molecules, cells, and networks throughout the lifespan, (2) cutting edge imaging technologies and studies of the physiology of aging, (3) translational application of neuroimaging, and (4) emerging technologies in the private sector.

This volume is the proceedings of a meeting that celebrated the 25th anniversary of the American Federation for Aging Research and its longstanding history of philanthropy in the area of aging research.

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Produktdetails

• Annals of the New York Academy of Sciences Vol.1097
• Verlag: Blackwell Publishers
• Seitenzahl: 252
• Erscheinungstermin: 2. April 2007
• Englisch
• Abmessung: 229mm x 152mm x 17mm
• Gewicht: 510g
• ISBN-13: 9781573316590
• ISBN-10: 1573316598
• Artikelnr.: 22761340

Autorenporträt

Mony J. de Leon and Donald A. Snider are the authors of Imaging and the Aging Brain, Volume 1097, published by Wiley.

Inhaltsangabe

Foreword: Mony J. De Leon. Part I: In Vivo Imaging of Molecules
Cells
and Networks in Aging and Animal Models of Alzheimer's:. 1. Making New Memories: The Role of the Hippocampus in New Associative Learning: Wendy A. Suzuki. 2. Anatomical and Functional Phenotyping of Mice Models of Alzheimer's Disease by MR Microscopy: Helene Benveniste
Yu Ma
Jasbeer Dhawan
Andrew Gifford
S. David Smith
Igor Feinstein
Congwu Du
Samuel C. Grant
and Patrick R. Hof. 3. Various Dendritic Abnormalities Are Associated with Fibrillar Amyloid Deposits in Alzheimer's Disease: Jaime Grutzendler
Kathryn Helmin
Julia Tsai
and Wen-Biao Gan. 4. Two-Photon Imaging of Astrocytic Ca2+ Signaling and the Microvasculature in Experimental Mice Models of Alzheimer's Disease: Takahiro Takano
Xiaoning Han
Rashid Deane
Berislav Zlokovic
and Maiken Nedergaard. 5. Synaptic and Mitochondrial Morphometry Provides Structural Correlates of Successful Brain Aging: Carlo Bertoni-Freddari
Patrizia Fattoretti
Belinda Giorgetti
Yessica Grossi
Marta Balietti
Tiziana Casoli
Giuseppina Di Stefano
and Gemma Perretta. 6. Impaired Recognition Memory and Decreased Prefrontal Cortex Spine Density in Aged Female Rats: Maureen Wallace
Maya Frankfurt
Adolfo Arellanos
Tomoko Inagaki
and Victoria Luine. 7. Alzheimer Amyloid ß-Peptide A-ß25¿35 Blocks Adenylate Cyclase-Mediated Forms of Hippocampal Long-Term Potentiation: Blaine E. Bisel
Kristen M. Henkins
and Karen D. Parfitt. 8. Age-Related Changes in Neuronal Susceptibility to Damage: Comparison of the Retinal Ganglion Cells of Young and Old Mice Before and After Optic Nerve Crush: Ai Ling Wang
Ming Yuan
and Arthur H. Neufeld. Part II: In Vivo Imaging of Human Aging and the Transition to Cognitive Impairment:. 9. Top-Down Modulation and Normal Aging: Adam Gazzaley and Mark D'Esposito. 10. Brain Aging and Its Modifiers: Insights from in Vivo Neuromorphometry and Susceptibility Weighted Imaging: Naftali Raz
Karen M. Rodrigue
and E. Mark Haacke. 11. Linking Brain Imaging and Genomics in the Study of Alzheimer's Disease and Aging: Eric M. Reiman. 12. Imaging and CSF Studies in the Preclinical Diagnosis of Alzheimer's Disease: M. J. De Leon
L. Mosconi
K. Blennow
S. Desanti
R. Zinkowski
P. D. Mehta
D. Pratico
W. Tsui
L. A. Saint Louis
L. Sobanska
M. Brys
Y. Li
K. Rich
J. Rinne
and H. Rusinek. 13. Functional MRI Studies of Associative Encoding in Normal Aging
Mild Cognitive Impairment
and Alzheimer's Disease: Reisa Sperling. 14. Quantitative EEG and Electromagnetic Brain Imaging in Aging and in the Evolution of Dementia: Leslie S. Prichep. 15. [123I]5-IA-85380 SPECT Imaging of ß2-Nicotinic Acetylcholine Receptor Availability in the Aging Human Brain: Effie M. Mitsis
Kelly P. Cosgrove
Julie K. Staley
Erin B. Frohlich
Frederic Bois
Gilles D. Tamagnan
Kristina M. Estok
John P. Seibyl
and Christopher H. Van Dyck. 16. Role of Aerobic Fitness and Aging on Cerebral White Matter Integrity: Bonita L. Marks
David J. Madden
Barbara Bucur
James M. Provenzale
Leonard E. White
Roberto Cabeza
and Scott A. Huettel. 17. Age-Related Changes in Nociceptive Processing in the Human Brain: Raimi L. Quiton
Steven R. Roys
Jiachen Zhuo
Michael L. Keaser
Rao P. Gullapalli
and Joel D. Greenspan. 18. Magnetic Resonance Spectroscopy and Environmental Toxicant Exposure: Marc G. Weisskopf. Part III: Diagnostic Applications of Imaging to Alzheimer's Disease:. 19. Tracking Alzheimer's Disease: Paul M. Thompson
Kiralee M. Hayashi
Rebecca A. Dutton
Ming-Chang Chiang
Alex D. Leow
Elizabeth R. Sowell
Greig De Zubicaray
James T. Becker
Oscar L. Lopez
Howard J. Aizenstein
and Arthur W. Toga. 20. Shifting Paradigms in Dementia: Toward Stratification of Diagnosis and Treatment Using MRI: Wiesje M. Van Der Flier
Frederik Barkhof
and Philip Scheltens. 21. Imaging-Guided Microarray: Isolating Molecular Profiles That Dissociate Alzheimer's Disease from Normal Aging: Ana Carolina Pereira
William Wu
and Scott A. Small. 22. Fibrillar and Oligomeric ß-Amyloid as Distinct Local Biomarkers for Alzheimer's Disease: Michael C. Montalto
Gill Farrar
and Cristina Tan Hehir. 23. Diffusion Tensor Imaging of Normal Appearing White Matter and Its Correlation with Cognitive Functioning in Mild Cognitive Impairment and Alzheimer's Disease: Juebin Huang and Alexander P. Auchus. 24. Enhanced Ryanodine-Mediated Calcium Release in Mutant PS1-Expressing Alzheimer's Mouse Models: Grace E. Stutzmann
Ian Smith
Antonella Caccamo
Salvatore Oddo
Ian Parker
and Frank Laferla. 25. Prospects for Prediction: Ethics Analysis of Neuroimaging in Alzheimer's Disease: J. Illes
A. Rosen
M. Greicius
and E. Racine. Index of Contributors.