IMMUNE BIOMARKERS IN PREECLAMPSIA
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The study was carried out in Department of Biochemistry and Department of Obstetrics and Gynaecology, Pt. B.D. Sharma PGIMS, Rohtak, India. Serum IL-6, TNF- and TGF-beta levels were analyzed in serum and cord blood of 20 normotensive pregnant (group I) and 20 pregnant women with preeclampsia (group II). Findings of high Serum IL-6, TNF- and TGF-beta in preeclamptic women (both in maternal and cord blood) suggest a definite role of inflammatory response in the pathogenesis of preeclampsia and therefore, may be useful in diagnosing patients with preeclampsia and identifying future cardiovascular...
The study was carried out in Department of Biochemistry and Department of Obstetrics and Gynaecology, Pt. B.D. Sharma PGIMS, Rohtak, India. Serum IL-6, TNF- and TGF-beta levels were analyzed in serum and cord blood of 20 normotensive pregnant (group I) and 20 pregnant women with preeclampsia (group II). Findings of high Serum IL-6, TNF- and TGF-beta in preeclamptic women (both in maternal and cord blood) suggest a definite role of inflammatory response in the pathogenesis of preeclampsia and therefore, may be useful in diagnosing patients with preeclampsia and identifying future cardiovascular risk. There may be a place of anti-inflammatory agents in management of preeclampsia.
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