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The "Nile perch" Lates niloticus is an important food fish in tropical and semitropical waters. Lates niloticus is one of the most important economic species as food fish in Egypt and finds good marketing in the different parts of Egypt. During the last years with the development of industries and modern civilization, large amount of pollutants have been discharged into the Nile and the surrounding lakes. These pollutants not only affect the growth, health, and reproduction of economically important fishes. L. niloticus is one of those fishes, which were affected by environmental factors and its distribution was restricted only to Lake Nasser, Wadi El-Rayan, El-Salam Canal and sometimes the Nile River. On the other hand it disappeared from the most of north lakes i.e., Manzalah and Borollus and most of the Nile River. Thus, the present work was planned to carry out a detailed study of the reproductive processess of L. niloticus at different maturity stages during its reproductivecycle in natural habitat.