Immunophenotyping of mammary carcinoma - García Pérez, Raisel;Llanes García, LLanuris;Sarduy Rodríguez, Ridyl
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Introduction: Breast cancer constitutes a group of tumors that show a very diverse biological behavior and great clinical variability. Immunohistochemical classification has great utility in defining the treatment and prognosis of the disease.Objective: The aim of the present investigation was to classify breast carcinomas into immunophenotypes using immunohistochemical markers and to analyze the clinicopathological characteristics of the different immunophenotypes.Conclusions: breast carcinomas with triple negative and Her2/neu immunophenotypes present more unfavorable clinicopathologic and…mehr

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Produktbeschreibung
Introduction: Breast cancer constitutes a group of tumors that show a very diverse biological behavior and great clinical variability. Immunohistochemical classification has great utility in defining the treatment and prognosis of the disease.Objective: The aim of the present investigation was to classify breast carcinomas into immunophenotypes using immunohistochemical markers and to analyze the clinicopathological characteristics of the different immunophenotypes.Conclusions: breast carcinomas with triple negative and Her2/neu immunophenotypes present more unfavorable clinicopathologic and immunohistochemical characteristics that are related to a poorer prognosis while luminal A carcinomas manifest more favorable characteristics that translate into a better prognosis.
Autorenporträt
Spécialiste de premier degré en anatomie pathologique, professeur adjoint, département des sciences biomédicales et morphologiques de base, faculté de médecine, université des sciences médicales "Serafín Ruiz de Zárate Ruiz", Villa Clara, Cuba.