Minimally Invasive Direct Coronary Artery Bypass (MIDCAB) grafting attempts to achieve adequate coronary artery revascularization in a less invasive manner than Off Pump Coronary Artery Bypass (OPCAB) grafting. In MIDCAB surgery which has less ICU stay, faster recovery, less pain, improved pulmonary function, fewer post operative infection, less antibiotic use than off-pump coronary artery revascularization technique (OPCAB). Postoperative renal dysfunction is common and one of the serious complications of cardiac surgery. Renal dysfunction or failure occurs nearly in 8% of all patients undergoing myocardial revascularization. This study shows the early postoperative renal dysfunction is less in left mini-thoracotomy under direct vision in comparison to standard median sternotomy among the patients who underwent isolated coronary artery bypass graft (CABG) surgery. Although in 7th & 30th POD post-operative renal status is similar in both groups.