In-vitro Cytotoxic Activity of Nyctanthes arbortristis Extracts - J., Deepalakshmi;R., Lakshmi;M.N., Kathiravan
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The efficacy of N. arbortristis as an anticancer agent for HeLa cell lines and L132 cell lines was studied. In the present study, it was revealed that the minimum effective concentration of ethyl acetate extract of N. arbortristis was toxic to 50% HeLa cervical cancer cells was recorded (IC50) at a concentration 4.7µg/ml were as 50% human embryonic pulmonary epithelial cells L132 was recorded (IC50) at a concentration 56.35µg/ml. The phytoconstituents present in N. arbortristis ethyl acetate extract are predicted to be responsible for anticancer activity. The results obtained in the study, it…mehr

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Produktbeschreibung
The efficacy of N. arbortristis as an anticancer agent for HeLa cell lines and L132 cell lines was studied. In the present study, it was revealed that the minimum effective concentration of ethyl acetate extract of N. arbortristis was toxic to 50% HeLa cervical cancer cells was recorded (IC50) at a concentration 4.7µg/ml were as 50% human embryonic pulmonary epithelial cells L132 was recorded (IC50) at a concentration 56.35µg/ml. The phytoconstituents present in N. arbortristis ethyl acetate extract are predicted to be responsible for anticancer activity. The results obtained in the study, it was revealed that the plant extracts possess increased anti-cancer nature against HeLa cell lines compared to L132. In future the N. arbortristis can be considered to be an important pharmacophore.
Autorenporträt
Mrs. J. Deepalakshmi is currently working as Professor in PG & Research Department of Biochemistry, Mohamed Sathak College of Arts and Science, Sholinganallur, Chennai, Tamil Nadu, India. She has more than 18 years of teaching and research experience in life science fields. Her main research area is focused on industrial wastewater treatment.