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Traumatic shock, as one of the clinical forms of the first period of traumatic illness, still attracts the attention of theorists and clinicians. This is due to the constant increase in domestic, transport, industrial and other types of injuries. According to the UN, some 300,000 people worldwide die each year from trauma. Research by local and international scientists has shown that about 75% of those injured in severe trauma combine to die within the first 12 hours. High lethality in traumatic disease, tendency to increasing number and severity of mechanical injuries, dictate the necessity of fundamental study of pathogenetic mechanisms of formation and development of disorders of central hemodynamics and microcirculation, metabolic disorders, appearance and increase of functional insufficiency of vital organs. The above stated served as a reason for the purposeful study of this problem, in order to develop a new approach to the treatment of patients in traumatic shock by clinical and experimental research.