In the present era, where most of us spend 18-20 hours per day behind the closed doors which has unknown, invisible, and chronic exposure to the health which gives its result suddenly that there is no time to ascertain the cause of symptoms realized. Its impacts depend on the level of development i.e. rural and urbanized area. Indoor word assimilate not only houses but also offices, classrooms, bathrooms, restaurants, garage, etc. i.e. any space surrounded by concrete structure. It is seen that its impacts are more severe in case of more developed area rather than less developed. One of the major factors is the free space availability as in case of rural area it is less effective, because of large free space availability as comparison to urban areas.