Induction of experimental liver diseases - Hussein, Jihan;Anwar El-Banna, Mona;Metwally Morsy, Safaa
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Liver disorders lead to various pathological changes like fatty liver, increase in ROS or oxidative stress, necrosis of liver cells, hepatitis,steatosis, cholestasis, vascular lesions, and granuloma andveno-occlusive diseases, increase in the level of inflammatory markers, hepatocellular carcinoma which further produce portal hypertension and hepatic failure. Animal models serve as an important tool to identifying the cause of liver injury, pathogenesis. In this project, We highlighted on some chemicals-induced experimental liver diseases. From these using chemicals: Heavy metal , -Carbon…mehr

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Produktbeschreibung
Liver disorders lead to various pathological changes like fatty liver, increase in ROS or oxidative stress, necrosis of liver cells, hepatitis,steatosis, cholestasis, vascular lesions, and granuloma andveno-occlusive diseases, increase in the level of inflammatory markers, hepatocellular carcinoma which further produce portal hypertension and hepatic failure. Animal models serve as an important tool to identifying the cause of liver injury, pathogenesis. In this project, We highlighted on some chemicals-induced experimental liver diseases. From these using chemicals: Heavy metal , -Carbon tetrachloride , Alcohol, -paracetamol , D-Galactosamine hydrochloride (DGa1N) and lipopolysaccharide (LPS). DGa1N and LPS together give us an experimental model of liver hepatitis that much like viral hepatitis in humans from both morphological and functional points of view.
Autorenporträt
Jihan Seid Hussein , Professor de Bioquímica Médica, Centro Nacional de Investigação, Giza, Egipto. Membro de várias sociedades científicas internacionais, recebeu um prémio de incentivo científico em Biotecnologia do Centro Nacional de Investigação em 2011. Recebeu um Prémio de Excelência Científica para os anos 2009-2016 ,Mais de 100 trabalhos internacionais.