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This issue of Immunology and Allergy Clinics, Guest Edited by Dr. Mitchell Grayson, is devoted to Infections and Asthma. Articles in this issue include: Epidemiology of Infections and Development of Asthma; Mechanisms of Respiratory Syncytial Virus Induced Asthma; Importance of Viral Characteristics in Respiratory Syncytial Virus Induced Disease; Human Rhinovirus and Asthma Exacerbation; Rhinovirus Attributes That Contribute to Asthma; Infant Immune Response to Respiratory Viral Infections; The Role of Bacteria in Asthma Pathogenesis; Beyond RSV and RV in the Pathogenesis and Exacerbation of Asthma; Biologics for Asthma and Risk of Infection: Should We Be Concerned?; Sinus Infections and Asthma; Helminths and Asthma: Friend or Foe?; and Primary Infection Prevention Strategies for Asthma.