B. Anderson, Roy M. Anderson, Pamela Anderson Lee

Infectious Diseases of Humans

Dynamics and Control

• Broschiertes Buch

Produktbeschreibung

Much-acclaimed, this book is now available in paperback. It provides an analytical framework for evaluating public health measures aimed at eradicating or controlling communicable diseases, such as malaria, measles, river blindness, sleeping sickness, schistosomiasis, and AIDS. The authors are leaders in the field. Their distinctive contribution has been to show the practice and far-reaching power of mathematical modelling in epidemiology, fully set out here for the first time.

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This book deals with infectious diseases -- viral, bacterial, protozoan and helminth -- in terms of the dynamics of their interaction with host populations. The book combines mathematical models with extensive use of epidemiological and other data. This analytic framework is highly useful for the evaluation of public health strategies aimed at controlling or eradicating particular infections. Such a framework is increasingly important in light of the widespread concern for primary health care programs aimed at such diseases as measles, malaria, river blindness, sleeping sickness, and schistosomiasis, and the advent of AIDS/HIV and other emerging viruses. Throughout the book, the mathematics is used as a tool for thinking clearly about fundamental and applied problems having to do with infectious diseases. The book is divided into two parts, one dealing with microparasites (viruses, bacteria and protozoans) and the other with macroparasites (helminths and parasitic arthropods). Each part begins with simple models, developed in a biologically intuitive way, and then goes on to develop more complicated and realistic models as tools for public health planning. The book synthesizes previous work in this rapidly growing field (much of which is scattered between the ecological and the medical literature) with a good deal of new material.

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Produktdetails

• Verlag: OUP Oxford
• Seitenzahl: 768
• Erscheinungstermin: 1. Januar 1992
• Englisch
• Abmessung: 234mm x 156mm x 41mm
• Gewicht: 1144g
• ISBN-13: 9780198540403
• ISBN-10: 019854040X
• Artikelnr.: 21093308

Inhaltsangabe

Introduction
1: A framework for discussing the population biology of infectious diseases
Part I: Microparasites
2: Biology of host-microparasite associations
3: The basic model: statics
4: Static aspects of eradication and control
5: The basic model: dynamics
6: Dynamic aspects of eradication and control
7: Beyond the basic model: empirical evidence of inhomogeneous mixing
8: Age-related transmission rates
9: Genetic heterogeneity
10: Social heterogeneity and sexually transmitted diseases
11: Spatial and other kinds of heterogeneity
12: Endemic infections in developing countries
13: Indirectly transmitted microparasites
Part II: Macroparasites: Biology of host-macroparasite associations
15: The basic model: statics
16: The basic model: dynamics
17: Acquired immunity
18: Heterogeneity within the human community
19: Indirectly transmitted helminths
20: Experimental epidemiology
21: Parasites, genetic variability, and drug resistance
22: The ecology and genetics of host-parasite associations
Appendices
References
Author index
Subject index