Darlen Calderin Jimenez, Lisania Reyes Espinosa, Carmen Viada González

Inflammation indices in prostate cancer patients

Inflammation indices as prognostic and predictive factors in prostate cancer patients

• Broschiertes Buch

Produktbeschreibung

Prostate cancer is the leading cause of worldwide incidence of neoplastic disease. On the other hand, inflammation plays a vital role in the spread of cancer cells. The aim of this work was to determine whether NLR and PLR inflammatory indices in prostate cancer patients have a prognostic value for survival and/or predictive of the effect of CIMAVAX-EGF and Nimotuzumab immunotherapy treatments. The results of the present investigation showed that the NLR index decreased and the PLR index increased over time for all treatments. A low NLR proved to be prognostic for the survival of patients in the CIMAvax-EGF trial. Also, the PLR index showed that its predictive value is due to the fact that patients with high PLR treated with Nimotuzumab have a longer survival than controls. The present work shows that the NLR and PLR indices are an accessible and cost-effective laboratory tool that provides prognostic and predictive information for prostate cancer and associated immunotherapeutictreatments.

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Produktdetails

• Verlag: Our Knowledge Publishing
• Seitenzahl: 72
• Erscheinungstermin: 9. November 2023
• Englisch
• Abmessung: 220mm x 150mm x 5mm
• Gewicht: 125g
• ISBN-13: 9786206653240
• ISBN-10: 6206653242
• Artikelnr.: 69419444

Autorenporträt

Licenciatura em Matemática, Universidade de Havana, 1991. Licenciatura em Cibernética, Universidade de Havana, 1995. Mestrado. Estatística e Probabilidade, Universidade de Havana, 2000 Investigador Assistente. 2002. Mestrado. Estatística Aplicada, Universidade de Hasselt, Bélgica, 2003. Tecnólogo de primeiro nível. 2010. Professor Assistente, 2015. Doutoramento em Ciências, 2022.