Inflammatory Disorders of the Nervous System

Pathogenesis, Immunology, and Clinical Management
Herausgegeben:Minagar, Alireza; Alezander, J. Steven

• Broschiertes Buch

Produktbeschreibung

Now well recognized, the critical role of the inflammatory response in the pathophysiology of peripheral and central neurological disorders, including Alzheimer's and Parkinson's diseases, is today the subject of intense investigation at the molecular level. In Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management, a panel of influential basic scientists review in detail the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidosis, HIV-associated dementia, and HTLV-associated neurological disorders.
Cutting-edge and authoritative, Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management offers basic research and clinical scientists an illuminating introduction to the new world of inflammatory CNS conditions and the emerging diagnostic and therapeutic opportunities they provide.

Produktdetails

• Current Clinical Neurology
• Verlag: Humana / Humana Press / Springer, Berlin
• Artikelnr. des Verlages: 978-1-61737-560-6
• Softcover reprint of hardcover 1st ed. 2005
• Seitenzahl: 362
• Erscheinungstermin: 19. November 2010
• Englisch
• Abmessung: 254mm x 178mm x 20mm
• Gewicht: 707g
• ISBN-13: 9781617375606
• ISBN-10: 1617375608
• Artikelnr.: 32208491

Inhaltsangabe

Endothelial Cell-Leukocyte Interactions During CNS Inflammation.- Multiple Sclerosis.- Cytokines and Brain.- Chemokines and Central Nervous System Disorders.- Circulating Cell-Derived Microparticles in Thrombotic and Inflammatory Disorders.- Multiple Sclerosis.- Neuroprotective Effects of Interferon-? in Multiple Sclerosis.- Acute Disseminated Encephalomyelitis.- Ingested Type I Interferon in Experimental Autoimmune Encephalomyelitis.- Neuromyelitis Optica.- Transverse Myelitis.- Optic Neuritis.- Central Nervous System Vasculitis.- Neurosarcoidosis.- Neuropsychiatric SLE.- Gene Expression in HIV-Associated Dementia.- Human T-Lymphotropic Virus-Associated Neurological Disorders.- West Nile Virus Infection of the Nervous System.

Rezensionen

From the reviews:

"The objective of this book is to provide the readers with a highly detailed review of the basic principles of neuroinflammation and extensive updates of the latest findings on common neuroinflammatory disorders. ... The treatment principles of the different inflammatory disorders are very well covered and up-to-date. This book can be of interest for the institutional library in order for doctors to look up specific details and treatment principles, and to enter deeply into neuroimmunological basics." (Orvar Eeg-Olofsson, European Journal of Paediatric Neurology, Vol. 11, June, 2007)