Private learning institutions in South Nyanza Region play a great role in the managerial use of cash management practices for proper usage of cash in learning institutions. Finance in learning institutions was an important constraint to growth in South Nyanza Region since these learning institutions do not get grant from the government sources such as free secondary education fund, free primary and government sponsored students. Leading to low enrollment turnout in the private sector therefore inadequacy in application of cash management practices. The purpose of the study was to determine the influence of cash management practices on performance of private learning institutions. This study determined to assess the influence of cash management practices on performance of learning institutions in South Nyanza Region. The specific objectives of the study were: to establish the influence of liquidity flow index on the performance of private learning institutions; to assess the influence of operation cash flows on performance of private learning institutions and to establish the influence of cash conversion cycle on performance of private learning institutions.