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This book consists of presentations made at the conference held on May 14-15, 2002 at the University of Missouri-Columbia, USA, by professionals from clinical areas, health care management, payer institutions, information technology industry, government and health care quality research. Chapters are a cross-section of various business perspectives of health information technologies. Together, they discuss the challenges facing the widespread implementation of information technology, possible solutions to economic, structural, cultural, and institutional barriers in the use of these technologies and present real-world examples of innovative information technologies that can be used as business models of applied clinical and business solutions to improve health care quality.