Fully updated with new research and discoveries since the last edition, this volume explores the relationship between the respiratory system and toxicology of inhaled substances. Filled with contributions from internationally recognized scientists from academic, industrial, and governmental sectors, the book presents chapters on the updated testing procedures and equipment guidelines for Europe and North America. This edition includes new material on nanoparticles, the use of microelectronics for studying inhalation toxicology, and emergency response strategies.
Fully updated with new research and discoveries since the last edition, this volume explores the relationship between the respiratory system and toxicology of inhaled substances. Filled with contributions from internationally recognized scientists from academic, industrial, and governmental sectors, the book presents chapters on the updated testing procedures and equipment guidelines for Europe and North America. This edition includes new material on nanoparticles, the use of microelectronics for studying inhalation toxicology, and emergency response strategies.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Harry Salem is the Chief Scientist at the U.S. Army Edgewood Chemical Biological Center. He has been a visiting professor at Drexel University, Rutgers University, Temple University, and the University of Pennsylvania and he has held a variety of positions in the pharmaceutical industry and in commercial toxicology laboratories. He was the editor-in-chief of the Journal of Applied Toxicology and is on the editorial board of the Journal of Inhalation Toxicology. He was the 2001 Society of Toxicology Congressional Science Fellow, and is a Fellow of the New York Academy of Sciences, the American College of Clinical Pharmacology, the American College of Toxicology, and the Academy of Toxicological Sciences. Sidney A. Katz is a professor of chemistry at Rutgers University. He has been a visiting professor in Canada, England, Germany, Hungary, Slovenia, and South Africa and has held research positions with E.I. duPont de Nemours and Company and with the R.M. Hollingshead Corporation. He has been a research fellow at the U.S. Army Edgewood Chemical Biological Center. His research activity is in environmental bioanalytical chemistry. From 1997 to 2002, he was a New Jersey commissioner for hazardous waste facilities siting.
Inhaltsangabe
Collection and Characterization of Particulate Matter Deposition. Nose-Only Aerosol Exposure Systems: Design, Operation, and Performance. Lungs-on-a-Chip. Human Health Risk Assessment of Inhaled Materials. Application of Inhalation Toxicology Concepts to Risk and Consequence Assessments. Time Scaling of Dose and Time to Response: The Toxic Load Exponent. Improper Use of Haber's Law Results in Erroneous Fatality Estimation from Predictive Models. Physiologically Based Kinetic Modeling of Inhalation. Nanomaterial Inhalation Exposure from Nanotechnology-Based Consumer Products. Influence of Physicochemical Properties on the Bioactivity of Carbon Nanotubes/Nanofibers and Metal Oxide Nanoparticles. Inhalation Toxicology of Riot Control Agents. Incapacitating Agents. Exposure to Ammonia. Serpentine and Amphibole Asbestos. Pulmonary Primary Cells Cocultured in a Novel Cell Culture System, the Integrated Discrete Multiple Cell-Type Coculture System (IdMOC): Pulmonary Cytotoxicity of Eight Cigarette Smoke Condensates and Nicotine. Animal Models of Chronic Obstructive Pulmonary Disease (COPD). Toxic Inhalation Injury: Management and Medical Treatment. Transcriptomic Responses to Crystalline Silica Exposure. Mechanisms Involved in the Inhalation Toxicity of Phosgene. Chemical Warfare Agents and Nuclear Weapons. Emergency Response Planning Guidelines. Safety Assessment of Therapeutic Agents Administered by the Respiratory Routes. Index.
Collection and Characterization of Particulate Matter Deposition. Nose-Only Aerosol Exposure Systems: Design, Operation, and Performance. Lungs-on-a-Chip. Human Health Risk Assessment of Inhaled Materials. Application of Inhalation Toxicology Concepts to Risk and Consequence Assessments. Time Scaling of Dose and Time to Response: The Toxic Load Exponent. Improper Use of Haber's Law Results in Erroneous Fatality Estimation from Predictive Models. Physiologically Based Kinetic Modeling of Inhalation. Nanomaterial Inhalation Exposure from Nanotechnology-Based Consumer Products. Influence of Physicochemical Properties on the Bioactivity of Carbon Nanotubes/Nanofibers and Metal Oxide Nanoparticles. Inhalation Toxicology of Riot Control Agents. Incapacitating Agents. Exposure to Ammonia. Serpentine and Amphibole Asbestos. Pulmonary Primary Cells Cocultured in a Novel Cell Culture System, the Integrated Discrete Multiple Cell-Type Coculture System (IdMOC): Pulmonary Cytotoxicity of Eight Cigarette Smoke Condensates and Nicotine. Animal Models of Chronic Obstructive Pulmonary Disease (COPD). Toxic Inhalation Injury: Management and Medical Treatment. Transcriptomic Responses to Crystalline Silica Exposure. Mechanisms Involved in the Inhalation Toxicity of Phosgene. Chemical Warfare Agents and Nuclear Weapons. Emergency Response Planning Guidelines. Safety Assessment of Therapeutic Agents Administered by the Respiratory Routes. Index.
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