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This issue of Thoracic Surgery Clinics of North America focuses on Innovations in Thoracic Surgery. Articles will include: Advances in Image Guided Thoracic Surgery; Evolving Applications of Extracorporeal Membrane Oxygenation (ECMO) in Thoracic Surgery; Novel Technologies for Isolated Lung Perfusion - Beyond Lung Transplant; Peroral Endoscopic Myotomy (POEM) for Achalasia; Bioengineered Organs: Dream or a Reality?; Credentialing for New Technology; Endoscopic Resection and Ablation for Early Stage Esophageal Cancer; Novel Technologies in Bronchoscopic Lung Volume Reduction; Advances in Uniportal Video-Assisted Thoracoscopic Surgery: Pushing the Envelope; Guided Bronchoscopy for Peripheral Pulmonary Nodules; Nanotechnology: Applications in Thoracic Surgery?; Present and Future Application of Energy Devices in Thoracic Surgery; and more!