The evidence based research findings of many fields like neuroscience, genetics and psychology, were filtered through the lens of education for exploring new challenges in teaching and learning process and finding ways to solve various educational problems, may it be learning disabilities, motivational problems, retention, development of thinking skills or similar sort of teaching-learning problems. The 7C's instructional model has been designed using the principles and instructional guidelines of Mind Brain and Education Science to focus on development of thinking skills among learners. The main objective of 7C's instructional model is to make the process of learning more meaningful and interesting to the learners by using positive emotions in teacher-student interactions and creating good learning environment. The effectiveness of 7C's instructional model is established in congruence to thinking pattern and parental cognitive stimulation. Thinking pattern has significantly improved with the use of instructional model in teaching Practices.