Content-based image retrieval is the set of techniques for retrieving relevant images from an image database on the basis of automatically derived image features. The need for efficient content-based image re trieval has increased tremendously in many application areas such as biomedicine, the military, commerce, education, and Web image clas sification and searching. In the biomedical domain, content-based im age retrieval can be used in patient digital libraries, clinical diagnosis, searching of 2-D electrophoresis gels, and pathology slides. I started my work on content-based image retrieval in 1995 when I was with Stanford University. The project was initiated by the Stan ford University Libraries and later funded by a research grant from the National Science Foundation. The goal was to design and implement a computer system capable of indexing and retrieving large collections of digitized multimedia data available in the libraries based on the media contents. At the time, itseemed reasonable to me that I should discover the solution to the image retrieval problem during the project. Experi ence has certainly demonstrated how far we are as yet from solving this basic problem.
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