As companies, industries and societies acknowledge sustainable development as a more rational paradigm than unconstrained growth; frameworks and tools are being developed and applied to perform the shift from the throughput economy towards a circular economy. This research proposes a model/tool for rapid assessment of regional material flow management potentials, in terms of optimisation possibilities of regional material and energy flows and stocks, with emphasis on associated Green House Gas emissions. Users of the model would be academic, research, planning, and management entities devoted to assess and streamline regional material and energy flows.