The book aims to offer to the teachers of the Agronomy career, in general, and to the teachers of the subject Applied Informatics, in particular, the theoretical references of epistemological, gnoseological, sociological, psychological and didactic character, assumed by the authors; as well as the arguments of the construction of a theoretical model of the process of interdisciplinary systematization of the contents of the subject Applied Informatics, where the essential theoretical aspects related to the process of establishment of interdisciplinary relations of the contents of this subject are exposed, revealing the treatment and the place that occupy in the process of formation of the professional in this career the dimensions Generalization, Transfer and interdisciplinary functional application of the contents of the referred subject. Finally, the revealed regularities of the process of theoretical construction of the interdisciplinary systematization of the content of the subject are exposed, which explain the movement and transformation of this process to a more essential level.