We live in a different world from that of only five or ten years ago, we are part of a historical period in transition between what has been and what will be, and we are actors in a world that is inexorably changing. In this context, the geographic distribution of natural resources, the levels of industrialization and technological progress that have been achieved are unparalleled in history. These and other facts and perceptions, such as those related to social, ethnic and religious differences, contribute to the emergence of various international conflicts. However, the way in which these differences are acted upon and managed will have an impact on their outcome and thus on the way of life of individuals and peoples in the coming decades. The topics of international relations and international negotiations covered in this book are dealt with in ten sections, which analyze trends, in some cases towards globalization and in others towards regionalization. It also considers some mechanisms that can help design the world of the future, from the strategic perspective of integral, territorial and sustainable development.