Intestinal Microbiota in Health and Disease

Modern Concepts
Herausgeber: Schiffrin, Eduardo J.; Brassart, Dominique; Marteau, Philippe

• Gebundenes Buch

Produktbeschreibung

Now considered an organ with defensive and metabolic capabilities, the intestinal microbiota plays a major role in the local host immune system development and education. It contributes to the generation of a homeostatic balance characterized by the capacity to react against pathogens while remaining hyperresponsive/tolerant against commensals. This homeostatic response depends on bacteria and bacterial product sensing by innate immune cells and their molecular asset at the intestinal mucosa. This book captures the enormous progress that has been accomplished in this field in recent years.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 346
• Erscheinungstermin: 11. Februar 2014
• Englisch
• Abmessung: 240mm x 161mm x 23mm
• Gewicht: 684g
• ISBN-13: 9781482226768
• ISBN-10: 1482226766
• Artikelnr.: 39185854

Autorenporträt

Eduardo J. Schiffrin, Philippe Marteau, Dominique Brassart

Inhaltsangabe

Commensal Intestinal Microbiota and Mucosal Immune System Development and
Function. Bacterial Imprinting of the Neonatal Immune System: Lessons From
Maternal Cells. Interactions of the Intestinal Microbiota with the
Epithelial Cells. Host Genotype, Environmental Factors and Microbiota
Composition. Pathogen-Host Cell Interactions at the Intestinal Level:
Lessons from Cultured Human Fully-Differentiated Colon Cancer Caco-2 and
T84 Epithelial Cell Lines. Manipulation of the Host-Cell Pathways by
Bacterial Entero-Pathogens. Use of Probiotic Cultures in Humans for the
Management of Gastrointestinal Infections. Composition of the Dominant
Microbiota During Flare-Ups and Remission of IBD. Opportunistic Pathogens
in IBD, and the Relation with Specific Gene Susceptibilities. Opportunistic
Pathogens in IBD, the Case of AIEC. Correction of Microbiota Disturbances
or Antagonism Against Specific Pathogens in IBD. Probiotics in IBD That Can
Modulate the Pathological Immune/Inflammatory Activation. Their Potential
Benefits in the Different Phases of the Disease. Fecal Microbiota in
Patients Receiving Enteral Nutrition. How to Preserve a Healthy Intestinal
Microbiota in the Intensive Care Patient. Dietary Factors, Microbiota in
Relation with Overweight and Diabetes.