Domschke

Intestinal Mucosa and its Diseases - Pathophysiology and Clinics

Herausgegeben:Domschke, W.; Stoll, R.; Brasitus, T. A.; Kagnoff, M. F.

• Gebundenes Buch

Produktbeschreibung

These proceedings of Falk Symposium 110 on `Intestinal Mucosa and its Diseases - Pathophysiology and Clinics' held at Titisee/Black Forest, Germany, 16-17 October 1998, comprehensively review salient clinical as well as scientific aspects - pending or settled - of the main intestinal diseases. In particular, chapters deal with infectious and neuroendocrine diarrhoeas, coeliac sprue, allergic enteropathy, intestinal lymphomas, colorectal carcinomas, and chronic inflammatory bowel diseases, in terms of clinical presentation as well as underlying mechanisms. This book therefore aims to bridge the gaps between basic science and clinics for the eventual treatment of patients afflicted with these diseases.

Produktdetails

• Falk Symposium 110
• Verlag: Springer / Springer Netherlands
• Artikelnr. des Verlages: 978-0-7923-8754-1
• 1999.
• Seitenzahl: 540
• Erscheinungstermin: 31. Juli 1999
• Englisch
• Abmessung: 241mm x 160mm x 34mm
• Gewicht: 930g
• ISBN-13: 9780792387541
• ISBN-10: 0792387546
• Artikelnr.: 23115317

Inhaltsangabe

List of Principal Authors. Preface. Section I: Epithelial Transport and
Diarrhoea. 1. Mechanisms of Intestinal Absorption and Secretion: An
abbreviated review and update; E.B. Chang, C. Bookstein. 2. Epithelial
Transport Changes in Experimental Inflammation; M.C. Berin, et al. 3.
Enteropathogens and the Epithelial Proinflammatory Program; M.F. Kagnoff,
L. Eckmann. 4. Enteropathogens and Diarrhae: The Role of Nerves and Mast
Cells in Toxin-Mediated Diarrheas; J.T. LaMont, C. Pothoulakis. 5.
Diarrhea in Neuroendocrine Disorders; R.T. Jensen. 6. Antidiarrheal
Therapy; G.J. Krejs. Section II: Transport Proteins and Intestinal
Diseases. 7. Molecular Cloning and Functional Analysis of Epithelial
Transporters: Renal Na+P1-cotransport as an Example; J. Biber, et al. 8.
Short-Term Regulation of NHE3 by Growth Factors/Protein Kinases Involves
Vesicle Trafficking in Epithelial Cells and Fibroblasts; M. Donowitz, et
al. 9. Towards Identification of the Molecular Mechanisms Involved in
Transcriptional Regulation of the Intestinal Na+/Glucose Cotransporter
(SGLT1); I.S. Wood, et al. 10. Iron Sensing and Regulation of Iron
Transport; A. Rolfs, M.A. Hediger. 11. Molecular Mechanisms of Intestinal
Calcium Absorption; M.D. Sitrin. 12. Peptide transport in the Small
Intestine; H. Daniel. Section III: Epithelial Development and
Differentiation. 13. Regulation of the Epithelial-Mesenchymal Cross-talk in
the Gut; M. Kedinger, et al. 14. Epithelial Differentiation and Adaptation
of the Intestine: Molecular Regulation; D.C. Rubin, et al. 15. NO as a
Modulator of Mucosal Barrier Function in the Intestine; P. Kubes. 16.
Function of Caudal-Related Homeobox Genes in the Intestinal Epithelium;
P.G. Traber. 17. The Role of COX-2 in Intestinal Cancer; C. Williams, et
al. 18. Mucin Gene Expression in the Gut; Y.S. Kim, et al. Section IV:
Mechanisms of Gastrointestinal Carcinogenesis. 19. New Pathoepigenetic
Aspects in GI Neoplasia &endash; State of the Art; T.A. Brasitus. 20. DNA
Mismatch Repair Genes and Colorectal Cancer; C.R. Boland, J.M. Carethers.
21. Metastatic Tumor Growth; M. Zöller. 22. Apoptosis, Differentiation and
the Control of Colonic Cell Numbers; A.C. Williams, et al. Section V:
Mucosal Structure and Function. 23. Pathobiology of Active Intestinal
Inflammation; J.L. Madara, D. Merlin. 24. Sampling and Antigen Presentation
Strategies in Mucosal Tissues; J.-P. Kraehenbuhl, et al. 25. Epithelial
Injury and Restitution; A.U. Dignas, et al. 26. Multi-step Assembly of the
Right Junction: Implications for Intestinal Barrier Regulation and Disease;
L.L. Mitic, et al. Section VI: New Insights into Small Intestinal
Diseases. 27. Immunobiology of Celiac Disease; M.F. Kagnoff. 28. Clinical
Problems in Coeliac Disease (CD); W.F. Caspary. 29. Functional Role of
Keratinocyte Growth Factor (KGF) and Transforming Growth Factor-alpha
(TGFalpha) in Mediating T-Cell-induced Crypt Cell Hyperplasia in the Gut;
M. Bajaj-Elliott, et al. 30. T- and B-Cell Lymphomas of the Intestine; M.
Zeitz. 31. Allergic Enteropathy; S.C. Bischoff, et al. 32. Mucosal Vaccines
and Oral Tolerance; J. Holmgren, et al. Section VII: Intestinal
Inflammation and Tumour Growth: Cell-Cell Interactions. 33. Healing
Gastrointestinal Mycosal Injury: Two Sides; D.K. Podolsky. 34.
Microvascular Endothelial Cells and Leukocyte Emigration; P. Brandtzaeg, et
al. 35. Epithelial Communication with Endothelial Cells &endash;
Implications for IBD? R. Stoll, et al. 36. Cell and Molecular Cross Talk in
Models of Mucosal Regeneration; F.C. Campbell, et al. 37. Novel Insights
into the Regulatory Role of MRP8 (S100A8) and MRP14 (S100A9) in the
Transendothelial Migration of Human Monocytes; C. Kerkhoff, et al. 38.
Mucosal Immune Lessons from Gene Targeting Experiments; T. Dassopoulos, et
al. Section VIII: Pathogenetic Mechanisms in Inflammatory Bowel Disease.
39. Experimental Models of Inflammation and their Relation to Human
Inflammatory Bowel Disease; W. Strober, IJ. Fuss. 40. Regulation of the
Inflammatory Response by Suppressor Cytokines; T. Kucharzik, et al. 41. A
Role for Mast Cells in Intestinal Inflammation; E. Saperas. 42.
Cytokine-Targeting Therapeutic Strategies in Inflammatory Bowel Disease;
S.J.H. van Deventer. 43. Current Concept of the Role of Intestinal
Lymphocyte Trafficking in the Organ-specific, Inflammation-related
Extraintestinal Manifestations of IBD; N. Lügering, et al. Index.