This book offers a comprehensive overview of the latest standard medical procedures and surgical techniques for biliary atresia (BA), as well as the perioperative care, long-term follow-up and transitions. Experts on pediatrics in such fields as hepatology, surgery, pathology, and liver transplantation present their research findings and analyses of this rare and intractable disease of unknown etiology. In Japan, shared experience and sound understanding based on conferences and guidelines have led to standardization of management and clinical care and, as a result, better…mehr
This book offers a comprehensive overview of the latest standard medical procedures and surgical techniques for biliary atresia (BA), as well as the perioperative care, long-term follow-up and transitions. Experts on pediatrics in such fields as hepatology, surgery, pathology, and liver transplantation present their research findings and analyses of this rare and intractable disease of unknown etiology. In Japan, shared experience and sound understanding based on conferences and guidelines have led to standardization of management and clinical care and, as a result, better outcomes.
Providing insights into improving surgical outcomes, and including special chapters focusing on social support systems for patients and families as well as recent advances in early diagnosis, this book a valuable resource for medical professionals around the globe who are involved in treating biliary atresia. It is especially useful for pediatric hepatologists, pediatric surgeons and transplant surgeons.
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Masaki Nio, M.D., Ph.D., ACSF Masaki Nio is Professor and Chief of Pediatric Surgery at Tohoku University Graduate School of Medicine and Director of Pediatric Medical Center of Tohoku University Hospital. In 1981, he completed a M.D. course at Tohoku University School of Medicine. In 1983, he joined the Second Department of Surgery, Tohoku University Hospital, which Professor Morio Kasai presided over from 1963 to 1986. In 1987, he completed a Ph.D. course in Pediatric Surgery at Tohoku University Graduate School of Medicine. From 1991 to 1993, he worked as a research fellow in Children's Hospital of Los Angeles, USA. He served as the President of Japanese Society of Pediatric Surgeons, a Board Member of Japan Surgical Society, a Board Member of Pacific Association of Pediatric Surgeons, the Chairman of Japanese Biliary Atresia Society, and so on. He has been a secretary general of Japanese Biliary Atresia Society since 2008.
Inhaltsangabe
Biliary Atresia: A Historical Overview.- History of The Japanese Biliary Atresia Society (JABS).- Japanese Biliary Atresia Registry (JBAR).- Pathogenesis: Overview.- Pathogenesis: Genetics/Epigenetics.- Pathogenesis: Viral Infection.- Pathogenesis: Maternal Microchimerism.- Epidemiology: Incidence and Gender Ratio.- Epidemiology: Ethnic Variations/Family Histories/Heredity.- Epidemiology: Gestational Age/Birth Weight /Associated Anomalies.- Classifications.- Mass Screening.- Stool Color Card System.- Prenatal Diagnosis and Signs/Symptoms.- Intracranial Hemorrhage.- Pathology.- Biomarkers.- Differential Diagnosis.- Diagnostic Modalities.- Preoperative Management and Direct Cholangiography.- Operative Procedures: Open Kasai Procedure.- Operative Procedures: Laparoscopic Kasai Procedure.- Operative Procedures: Re-do Kasai Procedure.- Operative Procedures: Cadaveric Liver Transplantation.- Operative Procedures: Living Donor Liver Transplantation.- Medical Treatment: UDCA/Steroid.- MedicalTreatment: Kampo Medicine.- Prevention/Treatment of Postoperative Cholangitis.- Nutritional Support.- Protocols of Follow-up Management.- Prognostic Indicators.- Long-term Complications: Gastro-Esophageal Varices.- Long-term Complications: Hypersplenism.- Long-term Complications: Cholangitis/Gall Stones.- Long-term Complications: Hepatopulmonary Syndrome.- Long-term Complications: Portopulmonary Hypertension.- Long-term Complications: Liver Cirrhosis/Hepatic Encephalopathy.- Long-Term Results, General.- Long-Term Results, Deformity of Intrahepatic Bile Ducts.- Long-Term Results, Social Performance.- Long-Term Results, Liver Transplantation.- Biliary Atresia and Pregnancy/Delivery.- Biliary Atresia and Malignancy.- Future Prospects.- Transition in Biliary Atresia.- Society of Patients and Families.- Clinical Guidelines for Biliary Atresia.