Douglas J Gelb
Introduction to Clinical Neurology
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Douglas J Gelb
Introduction to Clinical Neurology
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This book provides a systematic, logical, and practical approach to the diagnosis and management of common neurologic problems that clinicians are likely to encounter in a general medical practice. It covers all of the topics included in the Neurology Clerkship Core Curriculum.
This book provides a systematic, logical, and practical approach to the diagnosis and management of common neurologic problems that clinicians are likely to encounter in a general medical practice. It covers all of the topics included in the Neurology Clerkship Core Curriculum.
Produktdetails
- Produktdetails
- Verlag: Oxford University Press, USA
- 5th edition
- Seitenzahl: 544
- Erscheinungstermin: 10. Mai 2016
- Englisch
- Abmessung: 211mm x 137mm x 20mm
- Gewicht: 544g
- ISBN-13: 9780190467197
- ISBN-10: 0190467193
- Artikelnr.: 47864475
- Verlag: Oxford University Press, USA
- 5th edition
- Seitenzahl: 544
- Erscheinungstermin: 10. Mai 2016
- Englisch
- Abmessung: 211mm x 137mm x 20mm
- Gewicht: 544g
- ISBN-13: 9780190467197
- ISBN-10: 0190467193
- Artikelnr.: 47864475
Born in Minnesota, Douglas J. Gelb moved to Cambridge, MA for college (Harvard), Chicago, IL for medical and graduate school (University of Chicago), and San Francisco for internship and neurology residency (University of California, San Francisco). He did graduate research in human visual perception, but his clinical experiences in medical school and residency convinced him that his principal interests were patient care and teaching. In 1988, immediately after completing his residency, he moved to the University of Michigan and became the first faculty member in the Department of Neurology to be hired in the clinical academic track. At the University of Michigan, he directs the required third-year neurology clerkship and the second-year course on diseases of the nervous system. Nationally, he has been the Chair of the Consortium of Neurology Clerkship Directors and the Chair of the American Academy of Neurology A.B. Baker Section on Neurologic Education.
* Preface
* Preface to the First Edition
* Contributors
* Part I: The Basic Approach
* Chapter 1 Where's the Lesion?
* I. Sample Localization Problems
* II. The Game
* III. The Rules
* IV. The Play: The Long Version
* V. The Play: The Abbreviated Version
* VI. Rules for Speed Play
* Chapter 2 The Neurologic Examination
* I. More Localization Problems
* II. General Comments on the Neurologic Examination
* III. How to Do the Neurologic Examination
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* IV. Additional Comments on Terminology and Examination Technique
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* V. Interpretation of the Neurologic Examination
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* VI. Modi?cations of the Neurologic Examination
* A. Screening Neurologic Examination
* B. Examination of Stuporous or Comatose Patients
* VII. Discussion of Localization Problems
* Chapter 3 What's the Lesion?
* James W. Albers and Douglas J. Gelb
* I. Case History
* II. Beyond Localization
* A. Localization
* B. Temporal Pro?le
* C. Epidemiology
* III. Etiology
* A. Degenerative Diseases
* B. Neoplastic Diseases
* C. Vascular Diseases
* D. In?ammatory Diseases
* E. Toxic and Metabolic Diseases
* F. Traumatic Diseases
* G. Congenital and Developmental Diseases
* IV. Discussion of Case Histories
* Chapter 4 Stroke
* I. Case Histories
* II. Approach to Stroke
* III. Background Information
* A. De?nitions
* B. Classi?cation of Strokes by Etiology
* C. Pathophysiology
* IV. Diagnosis
* A. Clinical Features
* B. Imaging
* V. Management of Acute Stroke
* A. Restoration of Blood Flow in Ischemic Stroke
* B. Limitation of De?cits
* C. Rehabilitation
* VI. Primary Prevention
* A. Hypertension
* B. Smoking
* C. Diabetes
* D. Dyslipidemia
* E. Mechanical Heart Valves
* F. Atrial Fibrillation
* G. Carotid Stenosis
* H. Sickle Cell Disease
* I. Other Factors
* VII. Secondary Prevention of Ischemic Stroke
* A. Cardioembolic Disease
* B. Carotid Stenosis
* C. Anti-Platelet Medications
* D. Statin Therapy
* E. Risk Factor Modi?cation
* F. Stroke Mechanisms Other Than Cardioembolism and Carotid Stenosis
* G. Determining the Underlying Mechanism of Stroke
* VIII. Secondary Prevention of Cerebral Hemorrhage
* IX. Discussion of Case Histories
* Chapter 5 Seizures
* I. Case Histories
* II. Approach to Seizures
* III. Background Information
* A. De?nitions
* B. Clinical Characteristics of Seizures
* C. Seizures vs. Epilepsy
* D. Epilepsy Syndromes
* E. Electroencephalography
* F. Pathophysiology of Seizures and Epilepsy
* IV. Diagnosis
* A. Characterizing the Presenting Spell
* B. Identifying Prior Spells
* C. Recognizing Spells that are Not Seizures
* V. Determining the Cause of Seizures
* A. Provoked Seizures
* B. Epilepsy
* C. The Diagnostic Evaluation
* VI. Management of Seizures and Epilepsy
* A. Patients with Seizures but No Proven Epilepsy
* B. Patients with Epilepsy
* C. Patient Education (for Patients with Isolated Seizures or
Epilepsy)
* D. Restrictions (for Patients with Isolated Seizures or Epilepsy)
* VII. Special Clinical Problems
* A. Status Epilepticus
* B. Seizures and Pregnancy
* C. Refractory Seizures
* VIII. Discussion of Case Histories
* Chapter 6 Neuromuscular Disorders
* Mark B. Bromberg and Douglas J. Gelb
* I. Case Histories
* II. Approach to Neuromuscular Diseases
* III. Background Information
* A. Functional Divisions of the Peripheral Nervous System
* B. Proximal-to-Distal Organization of the Peripheral Nervous System
* C. Electrodiagnostic and Other Laboratory Studies
* IV. Speci?c Neuromuscular Diseases
* A. Motor Neuron Diseases
* B. Nerve Root Disorders (Radiculopathies)
* C. Plexus Disorders (Plexopathies)
* D. Peripheral Nerve Disorders (Neuropathies)
* E. Neuromuscular Junction Disorders
* F. Muscle Disorders (Myopathies)
* V. Symptomatic Treatment
* A. Emergency Measures
* B. Non-Urgent Measures: Motor Symptoms
* C. Non-Urgent Measures: Sensory Symptoms
* VI. Discussion of Case Histories
* Chapter 7 Dementing Illnesses
* I. Case Histories
* II. Approach to Dementing Illnesses
* A. Is It Abnormal?
* B. Is It Dementia?
* C. Is It Progressive?
* D. Is There a Potentially Reversible Cause?
* E. Which Diagnosis Is Most Likely?
* III. Primary Dementing Illnesses
* A. Alzheimer's Disease
* B. Dementia with Lewy Bodies (DLB)
* C. Frontotemporal Dementia (FTD)
* D. Vascular Dementia
* E. Normal Pressure Hydrocephalus (NPH)
* F. Creutzfeldt-Jakob Disease (CJD)
* G. Other Neurologic Diseases That Produce Dementia
* IV. Discussion of Case Histories
* Chapter 8 Movement Disorders
* I. Case Histories
* II. Approach to Movement Disorders
* III. Background Information
* A. Anatomic De?nitions
* B. Clinical De?nitions
* C. Classi?cation of Movement Disorders
* IV. Speci?c Movement Disorders
* A. Essential Tremor
* B. Parkinson's Disease
* C. Other Parkinsonian Syndromes
* D. Hereditary Ataxias
* E. Huntington's Disease
* F. Tardive Dyskinesia
* G. Dystonias
* H. Wilson's Disease
* I. Gilles de la Tourette's Syndrome
* V. Discussion of Case Histories
* Chapter 9 Sleep Disorders
* I. Case Histories
* II. Approach to Sleep Disorders
* III. Background Information
* A. De?nitions
* B. Sleep Physiology
* C. Diagnostic Tests
* D. Classi?cation of Sleep Disorders
* IV. Trouble Staying Awake
* A. Insuf?cient Sleep
* B. Sleep Apnea
* C. Narcolepsy
* D. Other Causes of Hypersomnolence
* V. Trouble Sleeping
* A. Sleep-Onset Delay
* B. Early Morning Awakening
* C. Sleep Fragmentation
* D. Sleep State Misperception
* VI. Abnormal Behavior During Sleep
* A. Nonrapid Eye Movement (NREM) Sleep Parasomnias
* B. Rapid Eye Movement (REM) Sleep Parasomnias
* VII. Discussion of Case Histories
* Chapter 10 Multifocal Central Nervous System Disorders
* I. Case Histories
* II. Approach to Multifocal Disorders
* III. Focal Diseases with Multifocal Propagation
* A. Metastatic Cancer
* B. Central Nervous System Infections
* IV. Inherently Multifocal Diseases
* A. Multiple Sclerosis
* B. Connective Tissue Diseases
* C. Sarcoidosis
* D. Coagulation Disorders
* V. Discussion of Case Histories
* Chapter 11 Acute Mental Status Changes
* I. Case Histories
* II. Background Information
* A. De?nitions
* B. Focal Mental Status Changes vs. Altered Level of Consciousness
* C. Physiology of Normal and Altered Consciousness
* III. Approach to Acute Changes in Level of Consciousness
* A. ABCs: Airway, Breathing, Circulation
* B. Oxygen, Glucose, Naloxone
* C. Pupils, Doll's Eyes, Motor Asymmetry
* D. Other Electrolytes, Renal, Hepatic, Temperature Abnormalities
* E. Everything Else
* IV. Special Circumstances
* A. Head Trauma
* B. Increased Intracranial Pressure
* C. Brain Death
* V. Discussion of Case Histories
* Chapter 12 Headache
* I. Case Histories
* II. Approach to Headache
* III. Background Information
* A. Primary vs. Secondary Headaches
* B. Pathophysiology of Migraine
* IV. Headache Emergencies: Subarachnoid Hemorrhage and Bacterial
Meningitis
* V. Other Secondary Headaches
* A. Viral Meningitis or Encephalitis
* B. Fungal or Tuberculous Meningitis
* C. Mass Lesions
* D. Giant Cell (Temporal) Arteritis
* E. Idiopathic Intracranial Hypertension (IIH; Pseudotumor Cerebri)
* F. Spontaneous Intracranial Hypotension
* G. Cerebral Venous Thrombosis
* H. Arterial Dissection
* I. Systemic Conditions
* J. Secondary Headache Syndromes with Diagnostic Ambiguity
* VI. Primary Headaches
* A. Migraine and Tension Headaches
* B. Cluster Headaches
* C. Trigeminal Neuralgia
* D. Glossopharyngeal Neuralgia
* E. Chronic Paroxysmal Hemicrania and Related Conditions
* F. Atypical Facial Pain
* VII. Discussion of Case Histories
* Chapter 13 Visual Symptoms
* I. Case Histories
* II. Background Information
* A. De?nitions
* B. Overview of the Visual System
* III. Approach to Visual Symptoms
* IV. Monocular Vision Loss
* A. Acute or Subacute Monocular Vision Loss in Young Patients
* B. Acute, Subacute, or Chronic Monocular Vision Loss in Older
Patients
* V. Transient Vision Loss (Monocular or Binocular)
* VI. Persistent Binocular Vision Loss
* VII. Diplopia
* A. Localization
* B. Differential Diagnosis and Management
* VIII. Discussion of Case Histories
* Chapter 14 Dizziness and Disequilibrium
* I. Case Histories
* II. Approach to Dizziness
* III. Localization
* IV. Differential Diagnosis
* V. Disequilibrium
* VI. Discussion of Case Histories
* Chapter 15 Back Pain and Neck Pain
* I. Case Histories
* II. Approach to Back or Neck Pain
* A. Emergency Situations
* B. Non-urgent Indications for Surgery
* III. Speci?c Conditions Causing Back or Neck Pain
* A. Musculoskeletal Pain
* B. Disc Herniation
* C. Spinal Stenosis
* IV. Discussion of Case Histories
* Chapter 16 Incontinence
* I. Case Histories
* II. Background Information
* III. Approach to Incontinence
* A. Neurologic vs. Urologic Causes of Incontinence
* B. Central vs. Peripheral Nervous System Causes of Incontinence
* IV. Discussion of Case Histories
* Chapter 17 Pediatric Neurology
* I. Case Histories
* II. Developmental Considerations
* III. Hypotonic Infants
* IV. Developmental Delay and Developmental Regression
* V. Paroxysmal Symptoms
* A. Headaches
* B. Seizures
* C. Breath-Holding Spells
* D. Benign Paroxysmal Vertigo
* VI. Gait Disturbance
* A. Spasticity
* B. Weakness
* C. Ataxia
* VII. Discussion of Case Histories
* Chapter 18 Geriatric Neurology
* I. Case Histories
* II. Geriatric Issues
* III. The Neurologic Examination in Normal Aging
* A. Mental Status
* B. Cranial Nerves
* C. Motor System
* D. Re?exes
* E. Sensation
* IV. Common Neurologic Symptoms in the Elderly
* A. Dizziness
* B. Gait Disturbance
* C. Incontinence
* D. Dementia
* E. Pain
* V. Discussion of Case Histories
* Chapter 19 Practice Cases
* I. Case Histories
* II. Answers
* Preface to the First Edition
* Contributors
* Part I: The Basic Approach
* Chapter 1 Where's the Lesion?
* I. Sample Localization Problems
* II. The Game
* III. The Rules
* IV. The Play: The Long Version
* V. The Play: The Abbreviated Version
* VI. Rules for Speed Play
* Chapter 2 The Neurologic Examination
* I. More Localization Problems
* II. General Comments on the Neurologic Examination
* III. How to Do the Neurologic Examination
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* IV. Additional Comments on Terminology and Examination Technique
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* V. Interpretation of the Neurologic Examination
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* VI. Modi?cations of the Neurologic Examination
* A. Screening Neurologic Examination
* B. Examination of Stuporous or Comatose Patients
* VII. Discussion of Localization Problems
* Chapter 3 What's the Lesion?
* James W. Albers and Douglas J. Gelb
* I. Case History
* II. Beyond Localization
* A. Localization
* B. Temporal Pro?le
* C. Epidemiology
* III. Etiology
* A. Degenerative Diseases
* B. Neoplastic Diseases
* C. Vascular Diseases
* D. In?ammatory Diseases
* E. Toxic and Metabolic Diseases
* F. Traumatic Diseases
* G. Congenital and Developmental Diseases
* IV. Discussion of Case Histories
* Chapter 4 Stroke
* I. Case Histories
* II. Approach to Stroke
* III. Background Information
* A. De?nitions
* B. Classi?cation of Strokes by Etiology
* C. Pathophysiology
* IV. Diagnosis
* A. Clinical Features
* B. Imaging
* V. Management of Acute Stroke
* A. Restoration of Blood Flow in Ischemic Stroke
* B. Limitation of De?cits
* C. Rehabilitation
* VI. Primary Prevention
* A. Hypertension
* B. Smoking
* C. Diabetes
* D. Dyslipidemia
* E. Mechanical Heart Valves
* F. Atrial Fibrillation
* G. Carotid Stenosis
* H. Sickle Cell Disease
* I. Other Factors
* VII. Secondary Prevention of Ischemic Stroke
* A. Cardioembolic Disease
* B. Carotid Stenosis
* C. Anti-Platelet Medications
* D. Statin Therapy
* E. Risk Factor Modi?cation
* F. Stroke Mechanisms Other Than Cardioembolism and Carotid Stenosis
* G. Determining the Underlying Mechanism of Stroke
* VIII. Secondary Prevention of Cerebral Hemorrhage
* IX. Discussion of Case Histories
* Chapter 5 Seizures
* I. Case Histories
* II. Approach to Seizures
* III. Background Information
* A. De?nitions
* B. Clinical Characteristics of Seizures
* C. Seizures vs. Epilepsy
* D. Epilepsy Syndromes
* E. Electroencephalography
* F. Pathophysiology of Seizures and Epilepsy
* IV. Diagnosis
* A. Characterizing the Presenting Spell
* B. Identifying Prior Spells
* C. Recognizing Spells that are Not Seizures
* V. Determining the Cause of Seizures
* A. Provoked Seizures
* B. Epilepsy
* C. The Diagnostic Evaluation
* VI. Management of Seizures and Epilepsy
* A. Patients with Seizures but No Proven Epilepsy
* B. Patients with Epilepsy
* C. Patient Education (for Patients with Isolated Seizures or
Epilepsy)
* D. Restrictions (for Patients with Isolated Seizures or Epilepsy)
* VII. Special Clinical Problems
* A. Status Epilepticus
* B. Seizures and Pregnancy
* C. Refractory Seizures
* VIII. Discussion of Case Histories
* Chapter 6 Neuromuscular Disorders
* Mark B. Bromberg and Douglas J. Gelb
* I. Case Histories
* II. Approach to Neuromuscular Diseases
* III. Background Information
* A. Functional Divisions of the Peripheral Nervous System
* B. Proximal-to-Distal Organization of the Peripheral Nervous System
* C. Electrodiagnostic and Other Laboratory Studies
* IV. Speci?c Neuromuscular Diseases
* A. Motor Neuron Diseases
* B. Nerve Root Disorders (Radiculopathies)
* C. Plexus Disorders (Plexopathies)
* D. Peripheral Nerve Disorders (Neuropathies)
* E. Neuromuscular Junction Disorders
* F. Muscle Disorders (Myopathies)
* V. Symptomatic Treatment
* A. Emergency Measures
* B. Non-Urgent Measures: Motor Symptoms
* C. Non-Urgent Measures: Sensory Symptoms
* VI. Discussion of Case Histories
* Chapter 7 Dementing Illnesses
* I. Case Histories
* II. Approach to Dementing Illnesses
* A. Is It Abnormal?
* B. Is It Dementia?
* C. Is It Progressive?
* D. Is There a Potentially Reversible Cause?
* E. Which Diagnosis Is Most Likely?
* III. Primary Dementing Illnesses
* A. Alzheimer's Disease
* B. Dementia with Lewy Bodies (DLB)
* C. Frontotemporal Dementia (FTD)
* D. Vascular Dementia
* E. Normal Pressure Hydrocephalus (NPH)
* F. Creutzfeldt-Jakob Disease (CJD)
* G. Other Neurologic Diseases That Produce Dementia
* IV. Discussion of Case Histories
* Chapter 8 Movement Disorders
* I. Case Histories
* II. Approach to Movement Disorders
* III. Background Information
* A. Anatomic De?nitions
* B. Clinical De?nitions
* C. Classi?cation of Movement Disorders
* IV. Speci?c Movement Disorders
* A. Essential Tremor
* B. Parkinson's Disease
* C. Other Parkinsonian Syndromes
* D. Hereditary Ataxias
* E. Huntington's Disease
* F. Tardive Dyskinesia
* G. Dystonias
* H. Wilson's Disease
* I. Gilles de la Tourette's Syndrome
* V. Discussion of Case Histories
* Chapter 9 Sleep Disorders
* I. Case Histories
* II. Approach to Sleep Disorders
* III. Background Information
* A. De?nitions
* B. Sleep Physiology
* C. Diagnostic Tests
* D. Classi?cation of Sleep Disorders
* IV. Trouble Staying Awake
* A. Insuf?cient Sleep
* B. Sleep Apnea
* C. Narcolepsy
* D. Other Causes of Hypersomnolence
* V. Trouble Sleeping
* A. Sleep-Onset Delay
* B. Early Morning Awakening
* C. Sleep Fragmentation
* D. Sleep State Misperception
* VI. Abnormal Behavior During Sleep
* A. Nonrapid Eye Movement (NREM) Sleep Parasomnias
* B. Rapid Eye Movement (REM) Sleep Parasomnias
* VII. Discussion of Case Histories
* Chapter 10 Multifocal Central Nervous System Disorders
* I. Case Histories
* II. Approach to Multifocal Disorders
* III. Focal Diseases with Multifocal Propagation
* A. Metastatic Cancer
* B. Central Nervous System Infections
* IV. Inherently Multifocal Diseases
* A. Multiple Sclerosis
* B. Connective Tissue Diseases
* C. Sarcoidosis
* D. Coagulation Disorders
* V. Discussion of Case Histories
* Chapter 11 Acute Mental Status Changes
* I. Case Histories
* II. Background Information
* A. De?nitions
* B. Focal Mental Status Changes vs. Altered Level of Consciousness
* C. Physiology of Normal and Altered Consciousness
* III. Approach to Acute Changes in Level of Consciousness
* A. ABCs: Airway, Breathing, Circulation
* B. Oxygen, Glucose, Naloxone
* C. Pupils, Doll's Eyes, Motor Asymmetry
* D. Other Electrolytes, Renal, Hepatic, Temperature Abnormalities
* E. Everything Else
* IV. Special Circumstances
* A. Head Trauma
* B. Increased Intracranial Pressure
* C. Brain Death
* V. Discussion of Case Histories
* Chapter 12 Headache
* I. Case Histories
* II. Approach to Headache
* III. Background Information
* A. Primary vs. Secondary Headaches
* B. Pathophysiology of Migraine
* IV. Headache Emergencies: Subarachnoid Hemorrhage and Bacterial
Meningitis
* V. Other Secondary Headaches
* A. Viral Meningitis or Encephalitis
* B. Fungal or Tuberculous Meningitis
* C. Mass Lesions
* D. Giant Cell (Temporal) Arteritis
* E. Idiopathic Intracranial Hypertension (IIH; Pseudotumor Cerebri)
* F. Spontaneous Intracranial Hypotension
* G. Cerebral Venous Thrombosis
* H. Arterial Dissection
* I. Systemic Conditions
* J. Secondary Headache Syndromes with Diagnostic Ambiguity
* VI. Primary Headaches
* A. Migraine and Tension Headaches
* B. Cluster Headaches
* C. Trigeminal Neuralgia
* D. Glossopharyngeal Neuralgia
* E. Chronic Paroxysmal Hemicrania and Related Conditions
* F. Atypical Facial Pain
* VII. Discussion of Case Histories
* Chapter 13 Visual Symptoms
* I. Case Histories
* II. Background Information
* A. De?nitions
* B. Overview of the Visual System
* III. Approach to Visual Symptoms
* IV. Monocular Vision Loss
* A. Acute or Subacute Monocular Vision Loss in Young Patients
* B. Acute, Subacute, or Chronic Monocular Vision Loss in Older
Patients
* V. Transient Vision Loss (Monocular or Binocular)
* VI. Persistent Binocular Vision Loss
* VII. Diplopia
* A. Localization
* B. Differential Diagnosis and Management
* VIII. Discussion of Case Histories
* Chapter 14 Dizziness and Disequilibrium
* I. Case Histories
* II. Approach to Dizziness
* III. Localization
* IV. Differential Diagnosis
* V. Disequilibrium
* VI. Discussion of Case Histories
* Chapter 15 Back Pain and Neck Pain
* I. Case Histories
* II. Approach to Back or Neck Pain
* A. Emergency Situations
* B. Non-urgent Indications for Surgery
* III. Speci?c Conditions Causing Back or Neck Pain
* A. Musculoskeletal Pain
* B. Disc Herniation
* C. Spinal Stenosis
* IV. Discussion of Case Histories
* Chapter 16 Incontinence
* I. Case Histories
* II. Background Information
* III. Approach to Incontinence
* A. Neurologic vs. Urologic Causes of Incontinence
* B. Central vs. Peripheral Nervous System Causes of Incontinence
* IV. Discussion of Case Histories
* Chapter 17 Pediatric Neurology
* I. Case Histories
* II. Developmental Considerations
* III. Hypotonic Infants
* IV. Developmental Delay and Developmental Regression
* V. Paroxysmal Symptoms
* A. Headaches
* B. Seizures
* C. Breath-Holding Spells
* D. Benign Paroxysmal Vertigo
* VI. Gait Disturbance
* A. Spasticity
* B. Weakness
* C. Ataxia
* VII. Discussion of Case Histories
* Chapter 18 Geriatric Neurology
* I. Case Histories
* II. Geriatric Issues
* III. The Neurologic Examination in Normal Aging
* A. Mental Status
* B. Cranial Nerves
* C. Motor System
* D. Re?exes
* E. Sensation
* IV. Common Neurologic Symptoms in the Elderly
* A. Dizziness
* B. Gait Disturbance
* C. Incontinence
* D. Dementia
* E. Pain
* V. Discussion of Case Histories
* Chapter 19 Practice Cases
* I. Case Histories
* II. Answers
* Preface
* Preface to the First Edition
* Contributors
* Part I: The Basic Approach
* Chapter 1 Where's the Lesion?
* I. Sample Localization Problems
* II. The Game
* III. The Rules
* IV. The Play: The Long Version
* V. The Play: The Abbreviated Version
* VI. Rules for Speed Play
* Chapter 2 The Neurologic Examination
* I. More Localization Problems
* II. General Comments on the Neurologic Examination
* III. How to Do the Neurologic Examination
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* IV. Additional Comments on Terminology and Examination Technique
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* V. Interpretation of the Neurologic Examination
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* VI. Modi?cations of the Neurologic Examination
* A. Screening Neurologic Examination
* B. Examination of Stuporous or Comatose Patients
* VII. Discussion of Localization Problems
* Chapter 3 What's the Lesion?
* James W. Albers and Douglas J. Gelb
* I. Case History
* II. Beyond Localization
* A. Localization
* B. Temporal Pro?le
* C. Epidemiology
* III. Etiology
* A. Degenerative Diseases
* B. Neoplastic Diseases
* C. Vascular Diseases
* D. In?ammatory Diseases
* E. Toxic and Metabolic Diseases
* F. Traumatic Diseases
* G. Congenital and Developmental Diseases
* IV. Discussion of Case Histories
* Chapter 4 Stroke
* I. Case Histories
* II. Approach to Stroke
* III. Background Information
* A. De?nitions
* B. Classi?cation of Strokes by Etiology
* C. Pathophysiology
* IV. Diagnosis
* A. Clinical Features
* B. Imaging
* V. Management of Acute Stroke
* A. Restoration of Blood Flow in Ischemic Stroke
* B. Limitation of De?cits
* C. Rehabilitation
* VI. Primary Prevention
* A. Hypertension
* B. Smoking
* C. Diabetes
* D. Dyslipidemia
* E. Mechanical Heart Valves
* F. Atrial Fibrillation
* G. Carotid Stenosis
* H. Sickle Cell Disease
* I. Other Factors
* VII. Secondary Prevention of Ischemic Stroke
* A. Cardioembolic Disease
* B. Carotid Stenosis
* C. Anti-Platelet Medications
* D. Statin Therapy
* E. Risk Factor Modi?cation
* F. Stroke Mechanisms Other Than Cardioembolism and Carotid Stenosis
* G. Determining the Underlying Mechanism of Stroke
* VIII. Secondary Prevention of Cerebral Hemorrhage
* IX. Discussion of Case Histories
* Chapter 5 Seizures
* I. Case Histories
* II. Approach to Seizures
* III. Background Information
* A. De?nitions
* B. Clinical Characteristics of Seizures
* C. Seizures vs. Epilepsy
* D. Epilepsy Syndromes
* E. Electroencephalography
* F. Pathophysiology of Seizures and Epilepsy
* IV. Diagnosis
* A. Characterizing the Presenting Spell
* B. Identifying Prior Spells
* C. Recognizing Spells that are Not Seizures
* V. Determining the Cause of Seizures
* A. Provoked Seizures
* B. Epilepsy
* C. The Diagnostic Evaluation
* VI. Management of Seizures and Epilepsy
* A. Patients with Seizures but No Proven Epilepsy
* B. Patients with Epilepsy
* C. Patient Education (for Patients with Isolated Seizures or
Epilepsy)
* D. Restrictions (for Patients with Isolated Seizures or Epilepsy)
* VII. Special Clinical Problems
* A. Status Epilepticus
* B. Seizures and Pregnancy
* C. Refractory Seizures
* VIII. Discussion of Case Histories
* Chapter 6 Neuromuscular Disorders
* Mark B. Bromberg and Douglas J. Gelb
* I. Case Histories
* II. Approach to Neuromuscular Diseases
* III. Background Information
* A. Functional Divisions of the Peripheral Nervous System
* B. Proximal-to-Distal Organization of the Peripheral Nervous System
* C. Electrodiagnostic and Other Laboratory Studies
* IV. Speci?c Neuromuscular Diseases
* A. Motor Neuron Diseases
* B. Nerve Root Disorders (Radiculopathies)
* C. Plexus Disorders (Plexopathies)
* D. Peripheral Nerve Disorders (Neuropathies)
* E. Neuromuscular Junction Disorders
* F. Muscle Disorders (Myopathies)
* V. Symptomatic Treatment
* A. Emergency Measures
* B. Non-Urgent Measures: Motor Symptoms
* C. Non-Urgent Measures: Sensory Symptoms
* VI. Discussion of Case Histories
* Chapter 7 Dementing Illnesses
* I. Case Histories
* II. Approach to Dementing Illnesses
* A. Is It Abnormal?
* B. Is It Dementia?
* C. Is It Progressive?
* D. Is There a Potentially Reversible Cause?
* E. Which Diagnosis Is Most Likely?
* III. Primary Dementing Illnesses
* A. Alzheimer's Disease
* B. Dementia with Lewy Bodies (DLB)
* C. Frontotemporal Dementia (FTD)
* D. Vascular Dementia
* E. Normal Pressure Hydrocephalus (NPH)
* F. Creutzfeldt-Jakob Disease (CJD)
* G. Other Neurologic Diseases That Produce Dementia
* IV. Discussion of Case Histories
* Chapter 8 Movement Disorders
* I. Case Histories
* II. Approach to Movement Disorders
* III. Background Information
* A. Anatomic De?nitions
* B. Clinical De?nitions
* C. Classi?cation of Movement Disorders
* IV. Speci?c Movement Disorders
* A. Essential Tremor
* B. Parkinson's Disease
* C. Other Parkinsonian Syndromes
* D. Hereditary Ataxias
* E. Huntington's Disease
* F. Tardive Dyskinesia
* G. Dystonias
* H. Wilson's Disease
* I. Gilles de la Tourette's Syndrome
* V. Discussion of Case Histories
* Chapter 9 Sleep Disorders
* I. Case Histories
* II. Approach to Sleep Disorders
* III. Background Information
* A. De?nitions
* B. Sleep Physiology
* C. Diagnostic Tests
* D. Classi?cation of Sleep Disorders
* IV. Trouble Staying Awake
* A. Insuf?cient Sleep
* B. Sleep Apnea
* C. Narcolepsy
* D. Other Causes of Hypersomnolence
* V. Trouble Sleeping
* A. Sleep-Onset Delay
* B. Early Morning Awakening
* C. Sleep Fragmentation
* D. Sleep State Misperception
* VI. Abnormal Behavior During Sleep
* A. Nonrapid Eye Movement (NREM) Sleep Parasomnias
* B. Rapid Eye Movement (REM) Sleep Parasomnias
* VII. Discussion of Case Histories
* Chapter 10 Multifocal Central Nervous System Disorders
* I. Case Histories
* II. Approach to Multifocal Disorders
* III. Focal Diseases with Multifocal Propagation
* A. Metastatic Cancer
* B. Central Nervous System Infections
* IV. Inherently Multifocal Diseases
* A. Multiple Sclerosis
* B. Connective Tissue Diseases
* C. Sarcoidosis
* D. Coagulation Disorders
* V. Discussion of Case Histories
* Chapter 11 Acute Mental Status Changes
* I. Case Histories
* II. Background Information
* A. De?nitions
* B. Focal Mental Status Changes vs. Altered Level of Consciousness
* C. Physiology of Normal and Altered Consciousness
* III. Approach to Acute Changes in Level of Consciousness
* A. ABCs: Airway, Breathing, Circulation
* B. Oxygen, Glucose, Naloxone
* C. Pupils, Doll's Eyes, Motor Asymmetry
* D. Other Electrolytes, Renal, Hepatic, Temperature Abnormalities
* E. Everything Else
* IV. Special Circumstances
* A. Head Trauma
* B. Increased Intracranial Pressure
* C. Brain Death
* V. Discussion of Case Histories
* Chapter 12 Headache
* I. Case Histories
* II. Approach to Headache
* III. Background Information
* A. Primary vs. Secondary Headaches
* B. Pathophysiology of Migraine
* IV. Headache Emergencies: Subarachnoid Hemorrhage and Bacterial
Meningitis
* V. Other Secondary Headaches
* A. Viral Meningitis or Encephalitis
* B. Fungal or Tuberculous Meningitis
* C. Mass Lesions
* D. Giant Cell (Temporal) Arteritis
* E. Idiopathic Intracranial Hypertension (IIH; Pseudotumor Cerebri)
* F. Spontaneous Intracranial Hypotension
* G. Cerebral Venous Thrombosis
* H. Arterial Dissection
* I. Systemic Conditions
* J. Secondary Headache Syndromes with Diagnostic Ambiguity
* VI. Primary Headaches
* A. Migraine and Tension Headaches
* B. Cluster Headaches
* C. Trigeminal Neuralgia
* D. Glossopharyngeal Neuralgia
* E. Chronic Paroxysmal Hemicrania and Related Conditions
* F. Atypical Facial Pain
* VII. Discussion of Case Histories
* Chapter 13 Visual Symptoms
* I. Case Histories
* II. Background Information
* A. De?nitions
* B. Overview of the Visual System
* III. Approach to Visual Symptoms
* IV. Monocular Vision Loss
* A. Acute or Subacute Monocular Vision Loss in Young Patients
* B. Acute, Subacute, or Chronic Monocular Vision Loss in Older
Patients
* V. Transient Vision Loss (Monocular or Binocular)
* VI. Persistent Binocular Vision Loss
* VII. Diplopia
* A. Localization
* B. Differential Diagnosis and Management
* VIII. Discussion of Case Histories
* Chapter 14 Dizziness and Disequilibrium
* I. Case Histories
* II. Approach to Dizziness
* III. Localization
* IV. Differential Diagnosis
* V. Disequilibrium
* VI. Discussion of Case Histories
* Chapter 15 Back Pain and Neck Pain
* I. Case Histories
* II. Approach to Back or Neck Pain
* A. Emergency Situations
* B. Non-urgent Indications for Surgery
* III. Speci?c Conditions Causing Back or Neck Pain
* A. Musculoskeletal Pain
* B. Disc Herniation
* C. Spinal Stenosis
* IV. Discussion of Case Histories
* Chapter 16 Incontinence
* I. Case Histories
* II. Background Information
* III. Approach to Incontinence
* A. Neurologic vs. Urologic Causes of Incontinence
* B. Central vs. Peripheral Nervous System Causes of Incontinence
* IV. Discussion of Case Histories
* Chapter 17 Pediatric Neurology
* I. Case Histories
* II. Developmental Considerations
* III. Hypotonic Infants
* IV. Developmental Delay and Developmental Regression
* V. Paroxysmal Symptoms
* A. Headaches
* B. Seizures
* C. Breath-Holding Spells
* D. Benign Paroxysmal Vertigo
* VI. Gait Disturbance
* A. Spasticity
* B. Weakness
* C. Ataxia
* VII. Discussion of Case Histories
* Chapter 18 Geriatric Neurology
* I. Case Histories
* II. Geriatric Issues
* III. The Neurologic Examination in Normal Aging
* A. Mental Status
* B. Cranial Nerves
* C. Motor System
* D. Re?exes
* E. Sensation
* IV. Common Neurologic Symptoms in the Elderly
* A. Dizziness
* B. Gait Disturbance
* C. Incontinence
* D. Dementia
* E. Pain
* V. Discussion of Case Histories
* Chapter 19 Practice Cases
* I. Case Histories
* II. Answers
* Preface to the First Edition
* Contributors
* Part I: The Basic Approach
* Chapter 1 Where's the Lesion?
* I. Sample Localization Problems
* II. The Game
* III. The Rules
* IV. The Play: The Long Version
* V. The Play: The Abbreviated Version
* VI. Rules for Speed Play
* Chapter 2 The Neurologic Examination
* I. More Localization Problems
* II. General Comments on the Neurologic Examination
* III. How to Do the Neurologic Examination
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* IV. Additional Comments on Terminology and Examination Technique
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* V. Interpretation of the Neurologic Examination
* A. Mental Status Examination
* B. Cranial Nerve Examination
* C. Motor Examination
* D. Re?ex Examination
* E. Sensory Examination
* VI. Modi?cations of the Neurologic Examination
* A. Screening Neurologic Examination
* B. Examination of Stuporous or Comatose Patients
* VII. Discussion of Localization Problems
* Chapter 3 What's the Lesion?
* James W. Albers and Douglas J. Gelb
* I. Case History
* II. Beyond Localization
* A. Localization
* B. Temporal Pro?le
* C. Epidemiology
* III. Etiology
* A. Degenerative Diseases
* B. Neoplastic Diseases
* C. Vascular Diseases
* D. In?ammatory Diseases
* E. Toxic and Metabolic Diseases
* F. Traumatic Diseases
* G. Congenital and Developmental Diseases
* IV. Discussion of Case Histories
* Chapter 4 Stroke
* I. Case Histories
* II. Approach to Stroke
* III. Background Information
* A. De?nitions
* B. Classi?cation of Strokes by Etiology
* C. Pathophysiology
* IV. Diagnosis
* A. Clinical Features
* B. Imaging
* V. Management of Acute Stroke
* A. Restoration of Blood Flow in Ischemic Stroke
* B. Limitation of De?cits
* C. Rehabilitation
* VI. Primary Prevention
* A. Hypertension
* B. Smoking
* C. Diabetes
* D. Dyslipidemia
* E. Mechanical Heart Valves
* F. Atrial Fibrillation
* G. Carotid Stenosis
* H. Sickle Cell Disease
* I. Other Factors
* VII. Secondary Prevention of Ischemic Stroke
* A. Cardioembolic Disease
* B. Carotid Stenosis
* C. Anti-Platelet Medications
* D. Statin Therapy
* E. Risk Factor Modi?cation
* F. Stroke Mechanisms Other Than Cardioembolism and Carotid Stenosis
* G. Determining the Underlying Mechanism of Stroke
* VIII. Secondary Prevention of Cerebral Hemorrhage
* IX. Discussion of Case Histories
* Chapter 5 Seizures
* I. Case Histories
* II. Approach to Seizures
* III. Background Information
* A. De?nitions
* B. Clinical Characteristics of Seizures
* C. Seizures vs. Epilepsy
* D. Epilepsy Syndromes
* E. Electroencephalography
* F. Pathophysiology of Seizures and Epilepsy
* IV. Diagnosis
* A. Characterizing the Presenting Spell
* B. Identifying Prior Spells
* C. Recognizing Spells that are Not Seizures
* V. Determining the Cause of Seizures
* A. Provoked Seizures
* B. Epilepsy
* C. The Diagnostic Evaluation
* VI. Management of Seizures and Epilepsy
* A. Patients with Seizures but No Proven Epilepsy
* B. Patients with Epilepsy
* C. Patient Education (for Patients with Isolated Seizures or
Epilepsy)
* D. Restrictions (for Patients with Isolated Seizures or Epilepsy)
* VII. Special Clinical Problems
* A. Status Epilepticus
* B. Seizures and Pregnancy
* C. Refractory Seizures
* VIII. Discussion of Case Histories
* Chapter 6 Neuromuscular Disorders
* Mark B. Bromberg and Douglas J. Gelb
* I. Case Histories
* II. Approach to Neuromuscular Diseases
* III. Background Information
* A. Functional Divisions of the Peripheral Nervous System
* B. Proximal-to-Distal Organization of the Peripheral Nervous System
* C. Electrodiagnostic and Other Laboratory Studies
* IV. Speci?c Neuromuscular Diseases
* A. Motor Neuron Diseases
* B. Nerve Root Disorders (Radiculopathies)
* C. Plexus Disorders (Plexopathies)
* D. Peripheral Nerve Disorders (Neuropathies)
* E. Neuromuscular Junction Disorders
* F. Muscle Disorders (Myopathies)
* V. Symptomatic Treatment
* A. Emergency Measures
* B. Non-Urgent Measures: Motor Symptoms
* C. Non-Urgent Measures: Sensory Symptoms
* VI. Discussion of Case Histories
* Chapter 7 Dementing Illnesses
* I. Case Histories
* II. Approach to Dementing Illnesses
* A. Is It Abnormal?
* B. Is It Dementia?
* C. Is It Progressive?
* D. Is There a Potentially Reversible Cause?
* E. Which Diagnosis Is Most Likely?
* III. Primary Dementing Illnesses
* A. Alzheimer's Disease
* B. Dementia with Lewy Bodies (DLB)
* C. Frontotemporal Dementia (FTD)
* D. Vascular Dementia
* E. Normal Pressure Hydrocephalus (NPH)
* F. Creutzfeldt-Jakob Disease (CJD)
* G. Other Neurologic Diseases That Produce Dementia
* IV. Discussion of Case Histories
* Chapter 8 Movement Disorders
* I. Case Histories
* II. Approach to Movement Disorders
* III. Background Information
* A. Anatomic De?nitions
* B. Clinical De?nitions
* C. Classi?cation of Movement Disorders
* IV. Speci?c Movement Disorders
* A. Essential Tremor
* B. Parkinson's Disease
* C. Other Parkinsonian Syndromes
* D. Hereditary Ataxias
* E. Huntington's Disease
* F. Tardive Dyskinesia
* G. Dystonias
* H. Wilson's Disease
* I. Gilles de la Tourette's Syndrome
* V. Discussion of Case Histories
* Chapter 9 Sleep Disorders
* I. Case Histories
* II. Approach to Sleep Disorders
* III. Background Information
* A. De?nitions
* B. Sleep Physiology
* C. Diagnostic Tests
* D. Classi?cation of Sleep Disorders
* IV. Trouble Staying Awake
* A. Insuf?cient Sleep
* B. Sleep Apnea
* C. Narcolepsy
* D. Other Causes of Hypersomnolence
* V. Trouble Sleeping
* A. Sleep-Onset Delay
* B. Early Morning Awakening
* C. Sleep Fragmentation
* D. Sleep State Misperception
* VI. Abnormal Behavior During Sleep
* A. Nonrapid Eye Movement (NREM) Sleep Parasomnias
* B. Rapid Eye Movement (REM) Sleep Parasomnias
* VII. Discussion of Case Histories
* Chapter 10 Multifocal Central Nervous System Disorders
* I. Case Histories
* II. Approach to Multifocal Disorders
* III. Focal Diseases with Multifocal Propagation
* A. Metastatic Cancer
* B. Central Nervous System Infections
* IV. Inherently Multifocal Diseases
* A. Multiple Sclerosis
* B. Connective Tissue Diseases
* C. Sarcoidosis
* D. Coagulation Disorders
* V. Discussion of Case Histories
* Chapter 11 Acute Mental Status Changes
* I. Case Histories
* II. Background Information
* A. De?nitions
* B. Focal Mental Status Changes vs. Altered Level of Consciousness
* C. Physiology of Normal and Altered Consciousness
* III. Approach to Acute Changes in Level of Consciousness
* A. ABCs: Airway, Breathing, Circulation
* B. Oxygen, Glucose, Naloxone
* C. Pupils, Doll's Eyes, Motor Asymmetry
* D. Other Electrolytes, Renal, Hepatic, Temperature Abnormalities
* E. Everything Else
* IV. Special Circumstances
* A. Head Trauma
* B. Increased Intracranial Pressure
* C. Brain Death
* V. Discussion of Case Histories
* Chapter 12 Headache
* I. Case Histories
* II. Approach to Headache
* III. Background Information
* A. Primary vs. Secondary Headaches
* B. Pathophysiology of Migraine
* IV. Headache Emergencies: Subarachnoid Hemorrhage and Bacterial
Meningitis
* V. Other Secondary Headaches
* A. Viral Meningitis or Encephalitis
* B. Fungal or Tuberculous Meningitis
* C. Mass Lesions
* D. Giant Cell (Temporal) Arteritis
* E. Idiopathic Intracranial Hypertension (IIH; Pseudotumor Cerebri)
* F. Spontaneous Intracranial Hypotension
* G. Cerebral Venous Thrombosis
* H. Arterial Dissection
* I. Systemic Conditions
* J. Secondary Headache Syndromes with Diagnostic Ambiguity
* VI. Primary Headaches
* A. Migraine and Tension Headaches
* B. Cluster Headaches
* C. Trigeminal Neuralgia
* D. Glossopharyngeal Neuralgia
* E. Chronic Paroxysmal Hemicrania and Related Conditions
* F. Atypical Facial Pain
* VII. Discussion of Case Histories
* Chapter 13 Visual Symptoms
* I. Case Histories
* II. Background Information
* A. De?nitions
* B. Overview of the Visual System
* III. Approach to Visual Symptoms
* IV. Monocular Vision Loss
* A. Acute or Subacute Monocular Vision Loss in Young Patients
* B. Acute, Subacute, or Chronic Monocular Vision Loss in Older
Patients
* V. Transient Vision Loss (Monocular or Binocular)
* VI. Persistent Binocular Vision Loss
* VII. Diplopia
* A. Localization
* B. Differential Diagnosis and Management
* VIII. Discussion of Case Histories
* Chapter 14 Dizziness and Disequilibrium
* I. Case Histories
* II. Approach to Dizziness
* III. Localization
* IV. Differential Diagnosis
* V. Disequilibrium
* VI. Discussion of Case Histories
* Chapter 15 Back Pain and Neck Pain
* I. Case Histories
* II. Approach to Back or Neck Pain
* A. Emergency Situations
* B. Non-urgent Indications for Surgery
* III. Speci?c Conditions Causing Back or Neck Pain
* A. Musculoskeletal Pain
* B. Disc Herniation
* C. Spinal Stenosis
* IV. Discussion of Case Histories
* Chapter 16 Incontinence
* I. Case Histories
* II. Background Information
* III. Approach to Incontinence
* A. Neurologic vs. Urologic Causes of Incontinence
* B. Central vs. Peripheral Nervous System Causes of Incontinence
* IV. Discussion of Case Histories
* Chapter 17 Pediatric Neurology
* I. Case Histories
* II. Developmental Considerations
* III. Hypotonic Infants
* IV. Developmental Delay and Developmental Regression
* V. Paroxysmal Symptoms
* A. Headaches
* B. Seizures
* C. Breath-Holding Spells
* D. Benign Paroxysmal Vertigo
* VI. Gait Disturbance
* A. Spasticity
* B. Weakness
* C. Ataxia
* VII. Discussion of Case Histories
* Chapter 18 Geriatric Neurology
* I. Case Histories
* II. Geriatric Issues
* III. The Neurologic Examination in Normal Aging
* A. Mental Status
* B. Cranial Nerves
* C. Motor System
* D. Re?exes
* E. Sensation
* IV. Common Neurologic Symptoms in the Elderly
* A. Dizziness
* B. Gait Disturbance
* C. Incontinence
* D. Dementia
* E. Pain
* V. Discussion of Case Histories
* Chapter 19 Practice Cases
* I. Case Histories
* II. Answers