Ulo Langel, Benjamin F. Cravatt, Astrid Graslund

Introduction to Peptides and Proteins

• Gebundenes Buch

Produktbeschreibung

Authored by key players in the field, this volume offers a relevant presentation of peptide and protein chemistry. It provides key insight into the fast-developing field of proteomics, including structural and functional aspects, biochip development, and clinical potential. It includes chapters on bioinformatics and proteomics and presents the latest information on concerns over protein degradation and the post-translational modifications of proteins and peptides. The book also includes a section on protein-coupled diseases that presents increasing evidence of the pathological impact of protein misfolding in relation to various neurodegenerative diseases, as well as a section on the role of proteins in cancer.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 440
• Erscheinungstermin: 18. November 2009
• Englisch
• Abmessung: 240mm x 161mm x 28mm
• Gewicht: 824g
• ISBN-13: 9781420064124
• ISBN-10: 1420064126
• Artikelnr.: 22824539

Autorenporträt

Langel, Ulo; Cravatt, Benjamin F.; Graslund, Astrid; von Heijne, N.G.H. ; Zorko, Matjaz; Land, Tiit; Niessen, Sherry

Inhaltsangabe

Introduction. Amino Acids. Noncovalent Interactions. Structural
Organization of Proteins. The Biosynthesis of Proteins. Posttranslational
Modifications. Protein Folding. Intracellular Sorting of Proteins. Protein
Turnover. Purification and Characterization of Proteins. Crystallography
and X-Ray Diffraction. Optical Spectroscopy. Nuclear Magnetic Resonance
(NMR). Methods to Follow Protein Folding. Mass Spectrometry. Chemical
Synthesis of Peptides and Proteins. Protein Engineering and Gene Silencing.
Protein-Ligand Interactions. Sequence Analysis and Function Prediction.
Protein Structure Prediction. Proteomics. Enzymes. Nucleic Acid-Binding
Proteins. Cell Surface Receptors and Signaling. Membrane Proteins.
Antibodies. Fibrous Proteins. Selected Classes of Bioactive Peptides.
Misfolding-Based Diseases. Miscleavage-Based Diseases. Missequence-Based
Diseases. Peptides and Proteins as Drugs.