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Now a day's research is concentrated towards the introduction of new and safe therapeutic agents of clinical importance. The success of imidazole as an important moiety of number of medicinal agents led to introduction of the triazoles. Triazoles nucleus have been incorporated into a wide variety of therapeutically interesting drug candidates including anti inflammatory, cns stimulants, sedatives, antianxiety and antimicrobial agents, Anti fungal activity. The Triazole derivative possess a wide a range of pharmacological such as antimicrobial, analgesic, anti- Inflammatory, anti convulsant, anti neoplastic, anti malarial, anti viral, anti proliferative, and anti cancer activities. The importance of triazole derivatives lies in the field that these have good position in heterocyclic chemistry, due to its various biological activities.