Sumaiya Nahid, Kishor Mazumder

Investigation of methanolic extract of Streblus asper Lour. barks

Phytochemical and in-vitro Pharmacological Screening

• Broschiertes Buch

Produktbeschreibung

The present study was carried out to investigate the Phytochemical and Pharmacological screening such as thrombolytic, cytotoxic, anti-inflammatory, antioxidant and antibacterial effect of crude methanol extract of Stem barks of Streblus asper L .(Family: Moraceae) and it¿s sub fractions such as N-hexane, Dichloromethane, Chloroform and Ethyl acetate extracts. Preliminary Phytochemical screening demonstrated the presence of Glycosides, Steroids, Saponins, Tannins and Resins. An in vitro thrombolytic activity on methanol, Dichloromethane and water extracts showed 13.071% (P = < 0.005), 23.319% (P = <0.005) and 31.28% (P = <0.0001) clot lyses respectively in different blood sample. The cytotoxic activity of the Streblus asper L. barks extracts of different fractions were assayed by ¿Brine shrimp lethality bioassay' method. In brine shrimp lethality bioassay, the Significant LC50 values of the methanol, chloroform, ethyl acetate were found 125.892¿g/ml, 100¿g/m1, 89.125¿g/m1 and LC90 were found 630.95¿g/ml, 562.34¿g/m1, 501.187¿g/m1 respectively indicating promising cytotoxic effect. The anti-inflammatory effect of the extracts was determined by egg albumin test.

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Produktdetails

• Verlag: LAP LAMBERT Academic Publishing
• Seitenzahl: 140
• Erscheinungstermin: 25. Oktober 2019
• Englisch
• Abmessung: 220mm x 150mm x 9mm
• Gewicht: 227g
• ISBN-13: 9786200291677
• ISBN-10: 6200291675
• Artikelnr.: 58283256

Autorenporträt

Sono Sumaiya Nahid, docente del dipartimento di Farmacia dell'Università di Scienze e Tecnologie di Chattagram, Bangladesh. I miei interessi di ricerca sono la progettazione di farmaci basati sulla struttura, l'isolamento guidato da biotest e lo screening farmacologico delle piante.