Ion and Molecule Transport in Lysosomes

Herausgeber: Gasnier, Bruno; Zhu, Michael X.

• Gebundenes Buch

Produktbeschreibung

This book discusses concepts and methods used to study lysosome ion and small molecule transport. The contents will not only attract accomplished investigators in need of a broad review and synthesis of this important subject but will also appeal to young investigators and trainees needing to acquire comprehensive knowledge and technical skills working with lysosomal ion channels and small molecule transporters.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 254
• Erscheinungstermin: 2. Juni 2020
• Englisch
• Abmessung: 240mm x 161mm x 18mm
• Gewicht: 549g
• ISBN-13: 9781138560390
• ISBN-10: 1138560391
• Artikelnr.: 69945876

Autorenporträt

Bruno Gasnier is CNRS Research Director, Group Leader at CNRS/Paris Descartes. Michael Xi Zhu is currently with the Department of Integrative Biology and Pharmacology at the University of Texas Health Science Center at Houston.

Inhaltsangabe

Preface. Editors. Contributors. Endosomal and Lysosomal Electrophysiology.
Chloride Transport across the Lysosomal Membrane. Endolysosomal Patch
Clamping: Approaches to Measure Vesicular Ion Channel Activities. TRPML
Subfamily of Endolysosomal Channels: Concepts and Methods. Investigating
the Role of Two-Pore Channel 2. (TPC2) in Zebrafish Neuromuscular
Development. Functional Study of Lysosomal Nutrient Transporters. Lysosomal
Vitamin B12. Trafficking. Detection of Lysosomal Membrane Permeabilization.
Rapid Isolation of Lysosomes from Cultured Cells Using a Twin Strep Tag. A
Transcriptomic Analysis and shRNA Screen for Intracellular Ion Channels and
Transporters Regulating Pigmentation. Index