Gustavo Oliveira Everton, Ana Patrícia Matos Pereira, Victor Elias Mouchrek Filho

Ixora coccinea L. : extracts and hydroalcoholic fractions

Antioxidant, anti-inflammatory and anti-arthritic potentials

• Broschiertes Buch

Produktbeschreibung

This study evaluated the antioxidant, anti-inflammatory and anti-arthritic properties of hydroalcoholic extracts and fractions of Ixora coccinea L. The hydroalcoholic extracts were obtained by maceration of Ixora coccinea flowers, and the fractions by liquid/liquid partition. Chemical characterization was performed by high performance liquid chromatography coupled with mass spectrometry (HPLC/MS). Assays were carried out to evaluate antioxidant, anti-inflammatory and anti-arthritic activity. The Effective Concentration - EC 50 was quantified to classify the potential of the chemical and biological activities evaluated. By HPLC/MS, catechol was quantified as the major component of the hydroalcoholic extract (59.50%). In the antioxidant assay, all the EC50 ranged between 6.45 and 87.15 ppm, classifying all the observed concentrations as very active. For the anti-inflammatory assay, the EC50 ranged from 32.27 to 198.06 ppm. For the anti-arthritic assay, the EC50 ranged from 10.76 to66.02 ppm.

Produktdetails

• Verlag: Our Knowledge Publishing
• Seitenzahl: 52
• Erscheinungstermin: 28. August 2023
• Englisch
• Abmessung: 220mm x 150mm x 4mm
• Gewicht: 96g
• ISBN-13: 9786206328230
• ISBN-10: 6206328236
• Artikelnr.: 68757937

Autorenporträt

Programma post-laurea in Chimica Associativa UFMA-IFMA (PPGDQUIM UFMA), Laboratorio per la Ricerca e l'Applicazione degli Oli Essenziali (LOEPAV/UFMA), São Luís, Maranhão, Brasile.