Collagen purified from marine sources proved as an effective bio molecule of pharmaceutical importance. In the present society, aging is widely associated with joint inflammation and disability (conditions of osteoarthritis, osteoporosis and osteopenia). In all cases it is common that there is progressive degeneration of glycoproteins and associated collagens in bone and joint tissues. Current options to promote joint comfort are limited to medicines that can reduce the symptoms like pain or inflammation and also have adverse health effects. The study confirms that the developed collagen product stimulates the joint matrix to re synthesize collagen and helping to maintain the structure of the joint and potentially aiding joint comfort. Also it is bio compatible, less immunogenic and can be used effectively for joint regenerative therapy.