Journeys in Pediatric Neuroblastoma Treatments - Foster, Jennifer; Kholodenko, I. V.; Smith, Valeria
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Journeys in Pediatric Neuroblastoma Treatments: Insights and Advances is a comprehensive collection of scientific journal articles that navigate the intricate landscape of neuroblastoma treatment. The foremost extracranial solid tumor in pediatric patients, neuroblastoma, presents diverse clinical challenges-from spontaneous regression to aggressive metastasis. This collection provides an in-depth exploration of the multifaceted approaches required for effective treatment. Readers will gain insights into the tri-phased treatment schema for high-risk neuroblastoma, including induction,…mehr

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Journeys in Pediatric Neuroblastoma Treatments: Insights and Advances is a comprehensive collection of scientific journal articles that navigate the intricate landscape of neuroblastoma treatment. The foremost extracranial solid tumor in pediatric patients, neuroblastoma, presents diverse clinical challenges-from spontaneous regression to aggressive metastasis. This collection provides an in-depth exploration of the multifaceted approaches required for effective treatment. Readers will gain insights into the tri-phased treatment schema for high-risk neuroblastoma, including induction, consolidation, and maintenance phases. Cutting-edge immunotherapy strategies, such as CAR T cell therapy and novel monoclonal antibodies, are extensively reviewed. Articles delve into molecular underpinnings, highlighting miRNA-targeted therapies and the potential of mesenchymal stromal cells in targeted treatment delivery and hematopoietic recovery. Groundbreaking approaches like targeted radiotherapy with 131I-metaiodobenzylguanidine (MIBG) and oncolytic virotherapy using the Zika virus are also discussed. With contributions that span genetic, molecular, and alternative treatment avenues, this compendium is an essential resource for researchers, clinicians, and students dedicated to advancing neuroblastoma treatment. Dive into the dynamic and hopeful trajectory of neuroblastoma research and discover the potential for improved outcomes and survival rates in pediatric oncology. Quality Research Publishing is dedicated to making knowledge more accessible to the general public by curating a topical compilation of the latest research on various subjects and providing plain language summaries. Each of the articles in this book is available individually and digitally without cost. However, we believe it is important for the contextualizing and sharing of educational and scientific work to curate this research in a way that is understandable and helpful to the average person seeking deeper knowledge of a particular subject. The research articles compiled for this book were published under a permissive Creative Commons license, are in the public domain, or have no copyright restrictions, permitting their use in this book. If you have questions about the licensing of any article, please visit qualityresearchpublishing.com.
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