Ketogenic Diet and Metabolic Therapies

Expanded Roles in Health and Disease
Herausgeber: Masino, Susan A

• Gebundenes Buch

Produktbeschreibung

Ketogenic Diet and Metabolic Therapies is the first comprehensive scientific resource on the ketogenic diet, covering the latest research including the biomedical mechanisms, established and emerging applications, metabolic alternatives, and implications for health and disease. Experts in clinical and basic research share their research into mechanisms spanning from ion channels to epigenetics, their insights based on decades of experience with the ketogenic diet inepilepsy, and their evidence for emerging applications ranging from autism to Alzheimer's disease to brain cancer. Research in metabolic therapies has spread into laboratories and clinics of every discipline, and is yielding to entirely new classes of drugs and treatment regimens.

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Produktdetails

• Verlag: Oxford University Press
• Seitenzahl: 424
• Erscheinungstermin: 17. November 2016
• Englisch
• Abmessung: 257mm x 183mm x 28mm
• Gewicht: 907g
• ISBN-13: 9780190497996
• ISBN-10: 0190497998
• Artikelnr.: 47863272

Autorenporträt

Susan A. Masino is the Vernon Roosa Professor of Applied Science and Professor of Psychology and Neuroscience at Trinity College. Her research is focused on adenosine, an endogenous molecule that promotes homeostasis and links between metabolism and brain activity. In 2008 she proposed that adenosine is a key mechanism underlying ketogenic diet therapy; based on this, her research spans multiple conditions. Dr. Masino is also dedicated to educational, environmental and public policy issues affecting brain health.

Inhaltsangabe

* Table of Contents * Preface * Contributors List * Section I Ketogenic Diet for Epilepsy in the Clinic * Eric Kossoff
MD
Section Editor * Chapter 1 Overview- Ketogenic Diets and Pediatric Epilepsy: An Update * Eric Kossoff
MD * Chapter 2 'Alternative' Ketogenic Diets * Elizabeth Neal
RD
MSc
PhD * Chapter 3 Dietary Therapy in Adults: History
Demand
and Results * Emily L. Johnson
MD and Mackenzie C. Cervenka
MD * Chapter 4 How Do You Implement the Diet? * Christina Bergqvist
MD * Chapter 5 Glut1 Deficiency and the KD * Joerg Klepper
MD
PhD * Chapter 6 Ketogenic Diet in Established Epilepsy Indications * Ann Bergin
MD
MB
ScM
MRCP * Chapter 7 Ketogenic Diet for Other Epilepsies * David T. Hsieh
MD and Elizabeth A. Thiele
MD
PhD * Chapter 8 The Ketogenic Diet and Related Therapies in "Novel" Situations: Idiopathic Generalized Epilepsy Syndromes * Sudha Kilaru Kessler MD
MSCE * Chapter 9 Ketogenic Diet in Status Epilepticus * Rima Nabbout
MD
PhD * Chapter 10 Preventing Side Effects and Diet Discontinuation * Cherie L. Herren
MD and Rana R. Said
MD * Section II Ketogenic Diet - Emerging Clinical Applications and Future Potential * Jong M. Rho
MD
Section Editor * Chapter 11 Overview: Expanded Uses of Ketogenic Therapies * Jong M. Rho
MD * Chapter 12 Metabolism-Based Treatments to Counter Cancer: Scientific Rationale * Thomas N. Seyfried
PhD and Laura Shelton
PhD * Chapter 13 Ketogenic Diet as Adjunctive Therapy for Malignant Brain Cancer * Eric C. Woolf
PhD and Adrienne C. Scheck
PhD * Chapter 14 Metabolic Therapy for Autism Spectrum Disorder and Co-Morbidities * Ning Cheng
PhD
Susan A. Masino
PhD
and Jong M. Rho
MD * Chapter 15 Glucose and Ketone Metabolism in the Aging Brain: Implications for Therapeutic Strategies to Delay the Progression of Alzheimer's Disease * Stephen C. Cunnane
PhD
Alexandre Courchesne-Loyer
MSc
Valerie St-Pierre
BSc
Camille Vandenberghe
PhD
Etienne Croteau
PhD
and Christian-Alexandre Castellano
PhD * Chapter 16 Ketogenic Diet and Ketones for the Treatment of Traumatic Brain and Spinal Cord Injury * Femke Streijger
PhD
Ward T. Plunet
PhD
and Wolfram Tetzlaff
MD
Dr.Med
PhD * Chapter 17 Anti-Inflammatory Effects of a Ketogenic Diet: Implications for New Indications * Nina Dupuis
PhD and Stéphane Auvin
MD
PhD * Chapter 18 Dietary Therapy for Neurological Disorders: Focus on Amyotrophic Lateral Sclerosis
Parkinson's Disease
Mood Disorders
and Migraine * Carl E. Stafstrom
MD
PhD * Section III Ketogenic Diet in the Laboratory * Detlev Boison
PhD Section Editor * Chapter 19 Overview of Ketogenic Diet in the Laboratory: Progress on Models and Mechanisms * Detlev Boison PhD * Chapter 20 Ketogenic Diet and PPARg * Timothy A. Simeone
PhD * Chapter 21 Ketogenic Diet in a Hippocampal Slice: Models and Mechanisms * Masahito Kawamura
Jr
PhD * Chapter 22 Metabolic Therapy and Pain * David N. Ruskin
PhD * Chapter 23 Ketogenic Diet
Adenosine
Epigenetics
and Antiepileptogenesis * Theresa A. Lusardi
PhD and Detlev Boison
PhD * Chapter 24 Ketogenic Diet
Aging
and Neurodegeneration * Kui Xu
MD
PhD
Joseph C. LaManna
PhD and Michelle A. Puchowicz
PhD * Chapter 25 Endocrine and Reproductive Effects of Ketogenic Diets * Jacob P. Harney
PhD
Kathryn Gudsnuk
MS
Ami Patel
MD Anantha R. Vellipuram
MD
Sathyajit Bandaru
MS and David Butler
MS * Chapter 26 Alzheimer's Disease: Causes and Treatment * Richard L. Veech
MD
PhD
DPhil and M. Todd King * Chapter 27 Mitigation of Damage from Reactive Oxygen Species and Ionizing Radiation by Ketone Body Esters * William Curtis
Martin Kemper
PhD
Alexandra Miller
PhD
Robert Pawlosky
PhD
M. Todd King
and Richard L. Veech
MD
PhD
DPhil * Chapter 28 Metabolic Seizure Resistance via BAD and KATP Channels * Juan Ramón Martínez-François
PhD
Nika Danial
PhD
and Gary Yellen
PhD * Chapter 29 Lactate Dehydrogenase: A Novel Metabolic Target * Nagisa Sada
PhD and Tsuyoshi Inoue
PhD * Chapter 30 Effects of the Ketogenic Diet on the Blood-Brain Barrier * Manoj Banjara
PhD and Damir Janigro
PhD * Section IV Ketone-Based Metabolism: General Health and Metabolic Alternatives * Dominic P. D'Agostino
PhD Section Editor * Chapter 31 Overview of Ketone-Based Metabolism: General Health and Metabolic Alternatives * Dominic P. D'Agostino
PhD * Chapter 32 Ketone Supplementation for Health and Disease * Angela M. Poff
PhD
Shannon L. Kesl
PhD
and Dominic P. D'Agostino
PhD * Chapter 33 Identifying the Molecular Mechanism of the MCT (Ketogenic) Diet * Matthew C. Walker
PhD and Robin S.B. Williams
PhD * Chapter 34 Triheptanoin in Epilepsy and Beyond * Karin Borges
PhD * Chapter 35 Amino Acids in the Treatment of Neurological Disorders * Adam L. Hartman
MD * Chapter 36 2-Deoxyglucose: Metabolic Control of Seizures through Inhibition of Glycolysis * Carl E. Stafstrom
MD
PhD and Thomas P. Sutula
MD
PhD * Chapter 37 Ketogenic Diets as Highly Effective Treatments for Diabetes Mellitus and Obesity * Eric C. Westman
MD
MHS
Emily Maguire
MSc
and William S. Yancy Jr.
MD
MHS * Chapter 38 Keto-Adaptation in Health and Fitness * Parker Hyde
CSCS
CISSN
Vincent J. Miller
PhD
and Jeff S. Volek
PhD
RD * Chapter 39 Advancing the Awareness and Application of Ketogenic Therapies Globally: The Charlie Foundation and Matthew's Friends * Beth Zupec-Kania
RD
CD
Jim Abrahams
Emma Williams
MBE
Susan A. Masino
PhD