Very little effort has been expended to prepare Iron(II) Schiff base amino acid complexes despite their importance as complexes containing a metal in unstable state, low oxidation state, as well as involving unstable ligands. Therefore, Some novel hydrophilic Fe(II) Schiff base amino acid complexes were prepared and characterized their structures by various methods to obtain more information and indicate their structures. Moreover, the antibacterial activity of the investigated complexes was screened against Gram-negative bacteria and Gram-positive bacteria. Furthermore, the kinetics of the acid hydrolysis of the prepared Fe(II) Schiff base amino acid complexes were carried out in aqueous, aqua-co organic media and in the presence of hydophilic and hydrophobic salts. This study has been carried out to gain more information about the new complexes and their reactivity.